Results 111 to 120 of about 5,926,013 (258)

Human immunodeficiency virus-1 core: The Trojan horse in virus-host interaction. [PDF]

Front Microbiol, 2022
Wang W, Li Y, Zhang Z, Wei W.
europepmc   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Viral Circular RNAs and Their Possible Roles in Virus-Host Interaction. [PDF]

Front Immunol, 2022
Zhang X, Liang Z, Wang C, Shen Z, Sun S, Gong C, Hu X.   +6 more
europepmc   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Epstein-Barr Virus LF2: an Antagonist to Type 1 Interferon [PDF]

, 2009
Upon viral infection, the major defense mounted by the host immune system is activation of the interferon (IFN)-mediated antiviral pathway, which is mediated by IFN regulatory factors (IRFs).
Shin, Young Chul, Johannsen, Eric, Haas, Juergen, Hyun Joo, Chul, Fossum, Even, Hutt-Fletcher, Lindsay M., Wu, L., Inn, Kyung-Soo, Jung, Jae U.   +8 more
core   +1 more source

Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver

Cells, 2019
Keratin proteins form intermediate filaments, which provide structural support for many tissues. Multiple keratin family members are reported to be associated with the progression of liver disease of multiple etiologies.
Volker Kinast, Stefan L. Leber, Richard J. P. Brown, Gabrielle Vieyres, Patrick Behrendt, Constanze Eßbach, Pavel Strnad, Florian W. R. Vondran, Markus Cornberg, Cora Wex, Thomas Pietschmann, Johannes Haybaeck, Daniel Todt, Eike Steinmann   +13 more
doaj   +1 more source

Editorial overview: 2022 "Virus-Host Interaction" section of Current Opinion in Virology. [PDF]

Curr Opin Virol, 2022
Gack MU, Baker SC.
europepmc   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Host-virus phylogeny congruence test for retroviruses.

, 2018
Host-virus phylogeny congruence test for retroviruses.
Guan-Zhu Han (155211), Huayao Zhao (5394599), Zhen Gong (292434), Xiaoyu Xu (356293)   +3 more
core   +1 more source

Analysis of poxvirus host cell entry by electron microscopy [PDF]

, 2013
Vaccinia virus (VACV) is the prototypic poxvirus and is complex in both composition and life cycle. In contrast to most viruses, poxviruses produce two types of infectious particles with different roles in virus dissemination: Mature virions (MVs ...
Bleck, Christopher Karl Ernst
core   +1 more source