Results 91 to 100 of about 5,926,013 (258)

Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host [PDF]

, 2013
Schmallenberg virus (SBV) is an emerging orthobunyavirus of ruminants associated with outbreaks of congenital malformations in aborted and stillborn animals.
Gerald Barry, Beer Martin, Kohl, Alain, Kerstin Hahn, Schnettler Esther, Alain Kohl, Glass, M., Barry Gerald, Lamm Catherine, Martin Beer, Vanessa Herder, Mcgregor, Eva, Piras, Ilaria M., Murgia, Claudio, Herder, V., Schnettler, E., Anna Janowicz, Lamm, C., Caporale Marco, Baumgärtner, Wolfgang., Shaw, Andrew, Murgia Claudio, McGregor Eva, Palmarini, Massimo, Melanie McFarlane, Janowicz, Anna, Piras, I.M., McFarlane, Melanie, Kohl Alain, Barry, Gerald, Janowicz, A., Schnettler, Esther, Claudio Murgia, McGregor, E., Piras Ilaria M., Lamm, Catherine, Beer, Martin, Eva McGregor, Hahn, K., Caporale, M., Baumgärtner, W., Catherine Lamm, Esther Schnettler, Kohl, A., Palmarini, M., Varela, M., Mandy Glass, Murgia, C., Baumgärtner Wolfgang, Mariana Varela, Janowicz Anna, Piras, Ilaria, Varela Mariana, Ilaria M Piras, Hahn, Kerstin, Shaw, A., Varela, Mariana, McFarlane Melanie, Herder Vanessa, McFarlane, M., Palmarini Massimo, Shaw Andrew, Herder, Vanessa, Wolfgang Baumgärtner, Glass, Mandy, Andrew Shaw, Baumgärtner, Wolfgang, Marco Caporale, Massimo Palmarini, Barry, G., Hahn Kerstin, Caporale, Marco, Glass Mandy   +72 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

A 28-Year History of HIV-1 Drug Resistance and Transmission in Washington, DC

Frontiers in Microbiology, 2019
Washington, DC consistently has one of the highest annual rates of new HIV-1 diagnoses in the United States over the last 10 years. To guide intervention and prevention strategies to combat DC HIV infection, it is helpful to understand HIV transmission ...
Keylie M. Gibson, Margaret C. Steiner, Seble Kassaye, Frank Maldarelli, Zehava Grossman, Zehava Grossman, Marcos Pérez-Losada, Marcos Pérez-Losada, Marcos Pérez-Losada, Keith A. Crandall, Keith A. Crandall   +10 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Lassa Virus Cell Entry Reveals New Aspects of Virus-Host Cell Interaction.

, 2017
Viral entry represents the first step of every viral infection and is a determinant for the host range and disease potential of a virus. Here, we review the latest developments on cell entry of the highly pathogenic Old World arenavirus Lassa virus ...
Torriani, G., Galan-Navarro, C., Kunz, S., Galan-Navarro C, Kunz S, Torriani G   +5 more
core   +1 more source

Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling [PDF]

, 2010
Chikungunya virus (CHIKV) is an emerging human pathogen transmitted by mosquitoes. Like that of other alphaviruses, CHIKV replication causes general host shutoff, leading to severe cytopathicity in mammalian cells, and inhibits the ability of infected ...
Ligtenberg, M., Suhrbier, A., Corinne Geertsema, Esther Schnettler, Fros, J., Just M. Vlak, Maarten Ligtenberg, Geertsema, C., Suhrbier, Andreas, Wen Jun Liu, Natalie A. Prow, Vlak, J.M., Dana L. Vanlandingham, Ligtenberg, Maarten, Khromykh, Alexander A., Jelke J. Fros, Vanlandingham, D.L., Vlak, Just M., Schnettler, E., Fros, J.J., Gorben P. Pijlman, Pijlman, G.P., Liu, W.J., Khromykh, A.A., Prow, A., Fros, Jelke J., Vanlandingham, Dana L., Liu, Wen Jun, Geertsema, Corinne, Prow, Natalie A., Alexander A. Khromykh, Schnettler, Esther, Pijlman, Gorben P., Andreas Suhrbier, Prow, N.A.   +34 more
core   +1 more source

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

Advanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang, Allison Madow, Jack Rudrum, Huaiyao Peng, Hao Nghi Luu, Peiyan Dong, Jifa Qi, Angela M. Belcher   +7 more
wiley   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Virogenomics: the virus-host interaction revisited

, 2008
Genomics tools allow us to assess gene expression 'genome wide' providing an unprecedented view on the host-side of the virus-host interaction. The success of the application of these tools crucially depends on our ability to reduce the total information
Andeweg, Arno, Osterhaus, Ab, Haagmans, Bart   +2 more
core   +1 more source

Life‐Like Ferrous Oxide Microspheres from Kombucha

Advanced Materials Interfaces, EarlyView.
Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis, Anna Nikolaidou, Andrew Adamatzky   +2 more
wiley   +1 more source