Results 101 to 110 of about 5,647,758 (266)

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Temporal Dynamics of Host Molecular Responses Differentiate Symptomatic and Asymptomatic Influenza A Infection. [PDF]

, 2011
Exposure to influenza viruses is necessary, but not sufficient, for healthy human hosts to develop symptomatic illness. The host response is an important determinant of disease progression.
Varkey, Jay B, Huang, Yongsheng, Kingsmore, Stephen, Hero Alfred O., Geoffrey S. Ginsburg, Dobigeon, Nicolas, Woolf Peter J., Varkey, Jay B., Christopher W. Woods, Woods Christopher W., Veldman Timothy, Woolf, Peter J., Timothy Veldman, Alfred O Hero, Kingsmore Stephen, Jay B Varkey, Micah T. McClain, McClain, Micah T., Zaas, Aimee K., Geoffrey S Ginsburg, Dobigeon Nicolas, Stephen Kingsmore, Øien N. Christine, Hero, Alfred O, Veldman, Timothy, McClain, Micah T, Woolf, Peter J, Zaas Aimee K., Yongsheng Huang, Christopher W Woods, Carin Lawrence, Carin, Lawrence, Ginsburg Geoffrey S., Oien, N. Christine, Nicholson, Bradley, Nicolas Dobigeon, Woods, Christopher W., Arvind Rao, N. Christine Øien, Rao, Arvind, Bradley Nicholson, Peter J Woolf, Woods, Christopher W, Lawrence Carin, Varkey Jay B., Aimee K. Zaas, Zaas, Aimee K, Rao Arvind, Aimee K Zaas, Øien, N Christine, McClain Micah T., Peter J. Woolf, Huang Yongsheng, Hero, Alfred O., Jay B. Varkey, Ginsburg, Geoffrey S, Alfred O. Hero, Nicholson Bradley, Ginsburg, Geoffrey S., Micah T McClain, N Christine Øien   +60 more
core   +2 more sources

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Generation of a mouse model for the in vivo study of HCV-host interaction [PDF]

, 2010
The natural species tropism of hepatitis C virus (HCV) is limited to humans and higher primates. Due to the limited availability of chimpanzees, the establishment of a small-animal model for the study of HCV infection has a high priority.
D'Angelo, Fulvio
core   +1 more source

COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms. [PDF]

Mol Syst Biol, 2021
Ostaszewski M, Niarakis A, Mazein A, Kuperstein I, Phair R, Orta-Resendiz A, Singh V, Aghamiri SS, Acencio ML, Glaab E, Ruepp A, Fobo G, Montrone C, Brauner B, Frishman G, Monraz Gómez LC, Somers J, Hoch M, Kumar Gupta S, Scheel J, Borlinghaus H, Czauderna T, Schreiber F, Montagud A, Ponce de Leon M, Funahashi A, Hiki Y, Hiroi N, Yamada TG, Dräger A, Renz A, Naveez M, Bocskei Z, Messina F, Börnigen D, Fergusson L, Conti M, Rameil M, Nakonecnij V, Vanhoefer J, Schmiester L, Wang M, Ackerman EE, Shoemaker JE, Zucker J, Oxford K, Teuton J, Kocakaya E, Summak GY, Hanspers K, Kutmon M, Coort S, Eijssen L, Ehrhart F, Rex DAB, Slenter D, Martens M, Pham N, Haw R, Jassal B, Matthews L, Orlic-Milacic M, Senff Ribeiro A, Rothfels K, Shamovsky V, Stephan R, Sevilla C, Varusai T, Ravel JM, Fraser R, Ortseifen V, Marchesi S, Gawron P, Smula E, Heirendt L, Satagopam V, Wu G, Riutta A, Golebiewski M, Owen S, Goble C, Hu X, Overall RW, Maier D, Bauch A, Gyori BM, Bachman JA, Vega C, Grouès V, Vazquez M, Porras P, Licata L, Iannuccelli M, Sacco F, Nesterova A, Yuryev A, de Waard A, Turei D, Luna A, Babur O, Soliman S, Valdeolivas A, Esteban-Medina M, Peña-Chilet M, Rian K, Helikar T, Puniya BL, Modos D, Treveil A, Olbei M, De Meulder B, Ballereau S, Dugourd A, Naldi A, Noël V, Calzone L, Sander C, Demir E, Korcsmaros T, Freeman TC, Augé F, Beckmann JS, Hasenauer J, Wolkenhauer O, Wilighagen EL, Pico AR, Evelo CT, Gillespie ME, Stein LD, Hermjakob H, D'Eustachio P, Saez-Rodriguez J, Dopazo J, Valencia A, Kitano H, Barillot E, Auffray C, Balling R, Schneider R, COVID-19 Disease Map Community.   +139 more
europepmc   +2 more sources

Interaction of Host Nucleolin with Influenza A Virus Nucleoprotein in the Early Phase of Infection Limits the Late Viral Gene Expression.

PLoS ONE, 2016
Influenza A virus nucleoprotein, is a multifunctional RNA-binding protein, encoded by segment-5 of the negative sense RNA genome. It serves as a key connector between the virus and the host during virus replication.
Deepshikha Kumar, Shobha Broor, Maitreyi S Rajala   +2 more
doaj   +1 more source

Insight on trans-plasma membrane behavior of virus-infected plant cells

Advances in Horticultural Science, 2017
Little is known about the ion fluxes generated during plant-virus interactions, despite significant losses caused by viruses to agricultural crops. Changes in average ion currents were identifying an early event in the signal transduction pathway related
A. Luvisi, E. Rinaldelli
doaj   +1 more source

The Battle for Survival: The Role of RNA Non-Canonical Tails in the Virus-Host Interaction. [PDF]

Metabolites, 2023
Wen X, Irshad A, Jin H.
europepmc   +1 more source

Defense pathways in Arabidopsis restricting compatible tobamoviruses during infection [PDF]

, 2014
Virus infected plants often develop strong disease symptoms including leaf deformation, chlorosis, necrosis and growth inhibition. In agriculture systems virus infection can lead to severe yield losses and a better understanding of plant defenses against
Kørner, Camilla Julie
core   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source