Results 191 to 200 of about 502,614 (287)

Peer Review #4 of "In silico predictions of protein interactions between Zika virus and human host (v0.3)"

, 2021

openalex   +1 more source

Antagonistic Ubiquitin Switching by USP7 and RNF40 Orchestrates KDM6A Homeostasis to License Coronavirus Susceptibility

Advanced Science, EarlyView.
We identify an antagonistic ubiquitin circuit that controls cellular permissiveness to multiple coronaviruses. The deubiquitinase USP7 stabilizes the epigenetic regulator KDM6A to upregulate viral receptors, while the E3 ligase RNF40 degrades KDM6A by catalyzing K6/K11‐ubiquitin chains of KDM6A for autophagic degradation.
Meng‐Zhuo Huang, Zhong‐Yuan Yang, Shi Wang, Yan Ge, Lan Lin, Mia Madel Alfajaro, Renata B. Filler, Wan‐Yao Song, Ming‐Zhu Kong, Jin Wei   +9 more
wiley   +1 more source

Virus-host interactions predictor (VHIP): Machine learning approach to resolve microbial virus-host interaction networks. [PDF]

PLoS Comput Biol
Bastien GE, Cable RN, Batterbee C, Wing AJ, Zaman L, Duhaime MB.   +5 more
europepmc   +1 more source

Interactions between cassava common mosaic virus TGBp1 and host MeGRXC3 proteins [PDF]

Qiuxian Xie, Yan FU, Shuming Bai, MengBin RUAN, Xiuchun ZHANG, Yanli REN   +5 more
openalex   +1 more source

Bifidobacterium Breve Yang08 Alleviates Atopic Dermatitis By Enriching Akkermansia Muciniphila and Inhibiting Neutrophil Extracellular Traps Formation In Mice

Advanced Science, EarlyView.
A novel Bifidobacterium breve strain, Yang08, is isolated to counter its depletion in atopic dermatitis. In mice, live Yang08 requires an intact gut microbiota to exert protection, specifically enriching Akkermansia muciniphila and potently inhibiting pathogenic neutrophil activation and NETosis in the skin.
Yanqiang Shi, Shuang He, Chengyi Li, Hung Chan, Zhenfeng Liu, Bin Yang, Qing Li   +6 more
wiley   +1 more source

Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV. [PDF]

Cell Discov, 2021
Yuan S, Liao G, Zhang M, Zhu Y, Xiao W, Wang K, Li C, Jia C, Sun N, Walch A, Gao D, Xu P, Deng Q, Zhang J, Wang H, Hu R.   +15 more
europepmc   +1 more source

Characterising of dengue virus’ (DENV’s) host interactions leading to dengue-induced microvascular leakage

Justin Duruanyanwu
openalex   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
wiley   +1 more source

Novel insights into human respiratory syncytial virus-host factor interactions through integrated proteomics and transcriptomics analysis

, 2016
Clyde Dapat, Hitoshi Oshitani
openalex   +2 more sources