Results 191 to 200 of about 487,341 (302)

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Current Perspectives on Functional Involvement of Micropeptides in Virus-Host Interactions. [PDF]

Int J Mol Sci
Sun H, Gu R, Tang T, Rai KR, Chen JL.
europepmc   +1 more source

Two-Color CRISPR Imaging Reveals Dynamics of Herpes Simplex Virus 1 Replication Compartments and Virus-Host Interactions. [PDF]

J Virol, 2022
Xu H, Wang J, Deng Y, Hou F, Fu Y, Chen S, Zou W, Pan D, Chen B.   +8 more
europepmc   +1 more source

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
wiley   +1 more source

Virus Budding/Host Interactions

Advances in Virology, 2011
Ronald N. Harty, Anthony P. Schmitt, Fadila Bouamr, Carolina B. Lopez, Claude Krummenacher   +4 more
doaj   +1 more source

Role of Extracellular Vesicles in Severe Dengue: Virus-Host Interactions and Biomarker Potential. [PDF]

Viruses
Agudelo JSH, Pereira G, Fernandes CJDC.
europepmc   +1 more source

PI3K/Akt/Nrf2 mediated cellular signaling and virus-host interactions: latest updates on the potential therapeutic management of SARS-CoV-2 infection. [PDF]

Front Mol Biosci, 2023
Lekshmi VS, Asha K, Sanicas M, Asi A, Arya UM, Kumar B.   +5 more
europepmc   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Metagenomic analysis reveals how multiple stressors disrupt virus-host interactions in multi-trophic freshwater mesocosms. [PDF]

Nat Commun
Wang T, Zhang P, Anantharaman K, Wang H, Zhang H, Zhang M, Xu J.   +6 more
europepmc   +1 more source

Investigating Virus-Host Interactions in Cultured Primary Honey Bee Cells. [PDF]

Insects, 2021
McMenamin AJ, Parekh F, Lawrence V, Flenniken ML.   +3 more
europepmc   +1 more source