Results 231 to 240 of about 5,037,554 (304)

Exploring Virus-Host Interactions Through Combined Proteomic Approaches Identifies BANF1 as a New Essential Factor for African Swine Fever Virus. [PDF]

Mol Cell Proteomics
Dupré J, Dolata KM, Pei G, Molouki A, Goatley LC, Küchler R, Soh TK, Bosse JB, Fablet A, Le Dimna M, Karadjian G, Hirchaud E, Netherton CL, Dixon LK, Reis AL, Vitour D, Le Potier MF, Karger A, Caignard G.   +18 more
europepmc   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Macrophage-augmented intestinal organoids model virus-host interactions in enteric viral diseases and facilitate therapeutic development. [PDF]

Nat Commun
Xu G, Zhou J, Liu K, Wang Y, Tsikari T, Qin F, van den Hil F, Boor PPC, Ayada I, de Vries AC, Li J, Jiang S, Offermans DM, Kainov DE, Janssen HLA, Peppelenbosch MP, Bijvelds MJC, Wang W, Orlova VV, Pan Q, Li P.   +20 more
europepmc   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

Editorial: Studying plant virus-host interactions: elucidating the natural resistance mechanism. [PDF]

Front Microbiol
Kumar RV, Gnanasekaran P.
europepmc   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Short-term virus-host interactions and functional dynamics in recently deglaciated Antarctic tundra soils. [PDF]

ISME Commun
Rubio-Portillo E, Arias-Real R, Rodríguez-Pérez E, Bañeras L, Antón J, de Los Ríos A.   +5 more
europepmc   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Correction to: Short-term virus-host interactions and functional dynamics in recently deglaciated Antarctic tundra soils. [PDF]

ISME Commun
europepmc   +1 more source

Dynamics of CRISPR-mediated virus-host interactions in the human gut microbiome. [PDF]

ISME J
López-Beltrán A, Botelho J, Iranzo J.
europepmc   +1 more source