Design and <i>in vitro</i> validation of Brome mosaic -virus-like particles for gene delivery and immunomodulation of melanoma. [PDF]
Elbadri K +12 more
europepmc +1 more source
Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley +1 more source
Engineering a streamlined virus-like particle for programmable tissue-specific gene delivery. [PDF]
Han J +5 more
europepmc +1 more source
From Copper Nanoparticles to Alumina Encapsulated Porous Layers With Enhanced Mechanical Stability
This study analyzes the synthesis‐structure relation of individual Cu nanoparticles and highly porous nanoparticle‐based Cu films using different sputtering‐based nanoparticle sources. The inherent mechanical instability of the films is tackled with Al2O3 encapsulation through atomic layer deposition, enabling 4‐fold increase in critical force in ...
Dominik Gutnik +6 more
wiley +1 more source
Glycosylated Foot-And-Mouth Disease Virus-Like Particles Produced in Pichia Pastoris Enhance Stability and Immunogenicity. [PDF]
Li Z +10 more
europepmc +1 more source
Using two‐photon polymerization of SU‐8 together with mold processing allowed the creation of defect‐free, flexible 3D microfluidic structures with sub‐micrometer precision in CYTOP. The fabricated CYTOP microfluidic chips enabled super‐resolution imaging of cancer cells in the microchannels, clearly visualizing previously undetectable fine structural ...
Koji Sugioka +16 more
wiley +1 more source
Identification of novel small chemical compounds that inhibit Ebola virus VP40-mediated virus-like particle production. [PDF]
Tsuruta T +4 more
europepmc +1 more source
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu +8 more
wiley +1 more source
Virus-like Particles and Spectral Flow Cytometry for Identification of Dengue Virus-Specific B Cells in Mice and Humans. [PDF]
Segura K +4 more
europepmc +1 more source
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali +4 more
wiley +1 more source

