Results 171 to 180 of about 6,581,491 (250)

PRELIMINARY INVESTIGATION OF GENETIC VARIABILITY OF GRAPEVINE LEAFROLL-ASSICIATED VIRUS 3 ISOLATED

, 2003
M. DIGIARO, G. P. MARTELLI, C. TURTURO, P. SALDARELLI, D. YAFENG, SAVINO, Vito Nicola   +5 more
core  

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Production of virus-like particles with AsCas12a nuclease and CMV-driven crRNA for mammalian genome editing. [PDF]

Front Genome Ed
Kruglova NA, Borovikova SE, Shepelev MV.
europepmc   +1 more source

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

Advanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu, Ruo‐xin Wang, Feng He, Qian Liu, Fu‐yin Li, Min Hui, Yu‐qian Shi, Yu Jiang, Qing‐hua Li, Jun‐wen Jing, Shi‐bin Yu, Li‐tian Ma, Qian‐nan Niu, Mian Zhang   +13 more
wiley   +1 more source

A Virus-Like-Particle-Based Conjugate Vaccine Targeting the Microtubule Binding Region of Tau Protein. [PDF]

ACS Omega
McFall-Boegeman H, Talbot C, Montalbano M, Puangmalai N, Wang KW, Kannan M, Shi J, Linning-Duffy K, Nick S, Yan L, Kuo MH, Kayed R, Huang X.   +12 more
europepmc   +1 more source

Detection of Plum bark necrosis stem pitting-associated virus (PBNSPaV) from different stone fruit species an optimisation of diagnostic tools

, 2003
A. MINAFRA, T. AMENDUNI, AMENDUNI T, C. HOBEIKA, SAVINO, Vito Nicola   +4 more
core  

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Taxonomy, complete nucleotide sequence and genome organization of grapevine leafroll-associated virus -7

, 2009
Martelli, Giovanni, Mikona, Cord, Rott, Michael E., Jelkmann, Wilhelm, Menzel, Wulf, Turturo, Camilla, Minafra, Angelantonio, Navarro, B.   +7 more
core  

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Advances in Engineered Virus-Like Particles for Genome Editing and Therapy. [PDF]

BioDrugs
Son SH, Woo S, Choi A, Ahn S, Yoo HC.
europepmc   +1 more source