Results 201 to 210 of about 6,581,491 (250)

Cryo-ET reveals distinct Gag lattice architectures in virus-like particles and immature HIV-1. [PDF]

Structure
Preece B, Peppel W, Durden H, Gallegos R, Clinger G, Bohn N, Huwendiek-Poser A, Ysassi G, Roman A, Garcia G, Cly T, Belnap D, Saffarian S.   +12 more
europepmc   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Engineering strategies and decision frameworks for virus-like particle-based vaccines against infectious diseases. [PDF]

Front Microbiol
Liu Y, Zhang Y, Liang L, Zhang H, Zhang T, Rong X, Tan J, Mi Y.   +7 more
europepmc   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Computational Identification of Dengue Virus MicroRNA-Like Structures and their Cellular Targets

Bioinformatics and Biology Insights, 2014
Maicol Ospina-Bedoya, Natalia Campillo-Pedroza, Juan P. Franco-Salazar, Juan C. Gallego-Gómez   +3 more
doaj  

Optimized lentivirus-derived virus-like particles for efficient delivery of Cas9-based genome editors. [PDF]

Nucleic Acids Res
Liu B, Klatt D, Harris C, McGuinness M, Brendel C, Williams DA.   +5 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Colloidal Crystallization of Virus-Like Particles with Polycations. [PDF]

Small
Tran B, Keys TG, Radiom M, Salentinig S.
europepmc   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Surface-Functionalization of PP7 Virus-Like Particles with Spytag for Bioconjugation Applications. [PDF]

Mol Biotechnol
Kheirvari M, Tumban E.
europepmc   +1 more source