Results 221 to 230 of about 6,581,491 (250)

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

Selective reactivation of latent HIV using CyclinT1-Tat-containing virus-like particles. [PDF]

Virology
Lavin TK, Tabler CO, Sweet TJ, Alhusaini N, Tilton JC.   +4 more
europepmc   +1 more source

Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection

Advanced Science, EarlyView.
Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse, Sixtine Coindre, Anne Wijkhuisen, Romain Marlin, Laure Fournier Le Ray, Juliette Pons, Melyssa Yaugel‐Novoa, Véronique Avettand‐Fenoel, Laurent Abi‐Rached, Anne‐Sophie Gallouet, Francis Relouzat, Mael Gourves, Asier Saez‐Cirion, Hisashi Arase, Gerard Zurawski, Sandra Zurawski, Nathalie Dereuddre‐Bosquet, Roger Le Grand, Stéphanie Simon, Olivier Lambotte, Benoit Favier   +20 more
wiley   +1 more source

Author Correction: Production of an immunogenic trivalent poliovirus virus-like particle vaccine candidate in yeast using controlled fermentation. [PDF]

NPJ Vaccines
Sherry L, Grehan K, Bahar MW, Swanson JJ, Fox H, Matthews S, Carlyle S, Qin L, Porta C, Wilkinson S, Robb S, Clark N, Liddell J, Fry EE, Stuart DI, Macadam AJ, Rowlands DJ, Stonehouse NJ.   +17 more
europepmc   +1 more source

Induction of neutralising antibodies against conserved rhinovirus capsid protein VP4 is dependent on presentation of VP4 peptide immunogens in a virus-like conformation. [PDF]

PLoS Pathog
Kelly JT, Dellosa GKY, Newman J, Mohamed AAM, Aniscenko J, Johnston SL, Schnell J, Tuthill TJ.   +7 more
europepmc   +1 more source

Foot-and-mouth disease virus-like particle mRNA vaccine induces strong humoral and cellular immunity. [PDF]

Appl Microbiol Biotechnol
Liu H, Zhang Y, Mu S, Hou F, Jiang L, Wang Z, Dong H, Mehdi MM, Guo H, Sun S.   +9 more
europepmc   +1 more source

Capsid flexibility during Ty1 virus-like particle assembly

Sibert BS, Hannon-Hatfield JA, Nicastro G, Cottee MA, Taylor IA, Garfinkel DJ, Wright ER.   +6 more
europepmc   +1 more source

A decoy virus strategy using plant-produced SARS-CoV-2 virus-like-particles to inhibit infection and lung injury. [PDF]

J Transl Med
Liang J, Onodera Y, Li Y, Wu J, McColman S, Cramb DT, Khang J, Khine AA, Chen YW, Rotstein OD, Mubareka S, Slutsky AS, Zhang H.   +12 more
europepmc   +1 more source

Downstream Purification Strategies for Virus-like Particles: A Systematic Review of Structure Preservation, Impurity Control, and Viral Safety. [PDF]

Microorganisms
Zhang J, Chen C.
europepmc   +1 more source

The Role of Counterions in the Assembly of Charged Virus-Like Shells. [PDF]

J Phys Chem B
Hsiao YW, Hedström M, Ryadnov MG, Bray DJ, Crain J.   +4 more
europepmc   +1 more source