Results 241 to 250 of about 1,082,836 (299)

Preclinical Assessment of a New Virus-like Particle-Based Quadrivalent Human Papillomavirus Vaccine in Animal Models. [PDF]

Vaccines (Basel)
Mohammadi Barzelighi H, Naderi Saffar Z, Pakatchian E, Taqavian M, Javadimehr B, Safaeian M, Abbaszadeh P, Jalili H.   +7 more
europepmc   +1 more source

Immunogenicity and efficacy of an mRNA vaccine expressing a virus-like particle spike antigen against SARS-CoV-2. [PDF]

NPJ Vaccines
Laliberte JP, Cai Y, Kenny T, Zhang Y, Ren K, Rosenthal K, Flores D, Roque R, Acton O, Peano VC, Janney N, Puri V, Siddiqui S, Pack A, Padilla G, Diallo S, Adissu H, Choudhary R, Pruitt H, Cheng YH, Thom G, Newton M, Kurokawa C, Guest J, Swanson P, Loo YM, Francica JR, Blair W, Esser M.   +28 more
europepmc   +1 more source

MS2 virus-like particles as a versatile platform for multi-disease vaccines: a review. [PDF]

Front Immunol
Zhou G, Luo Z, Zhang Z, Cao S, Li Y.
europepmc   +1 more source

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Virus-like particles as immunogens

Trends in Microbiology, 2003
Subunit vaccines based on recombinant proteins can suffer from poor immunogenicity owing to incorrect folding of the target protein or poor presentation to the immune system. Virus-like particles (VLPs) represent a specific class of subunit vaccine that mimic the structure of authentic virus particles.
Rob, Noad, Polly, Roy
openaire   +2 more sources

Hybrid Ty Virus-Like Particles

International Reviews of Immunology, 1994
Vaccines need to activate antigen presenting cells, overcome genetic restriction in T-cell responses and elicit both T and B memory cells. In order to produce recombinant vaccines which can do this, considerable effort has been put into developing particulate antigen presentation systems to generate polyvalent, high molecular weight antigens which ...
S E, Adams, N R, Burns, G T, Layton, A J, Kingsman   +3 more
openaire   +2 more sources

Virus-like particles in leukaemia

Experimental pathology, 1984
Hitherto intracytoplasmic virus-like particles have not been observed simultaneously in nucleus and cytoplasm in human lymphoblasts. We analysed 20 cases of lymphoblastic leukaemia in children and found some virus-like particles in cytoplasm (12 cases) and both in nucleus and cytoplasm (4 cases).
T, Slubowski, M, Kujawa
openaire   +2 more sources

Superfluorescent Virus-like Particles

OSA Advanced Photonics Congress 2021, 2021
After short pulse excitation, the optical emission from a dense array of fluorophores attached onto the surface of an icosahedral virus is strongly accelerated. Here we review the circumstances in which this intriguing phenomenon can be observed.
openaire   +1 more source

Enzyme Stabilization by Virus-Like Particles

Biochemistry, 2020
The properties of enzymes packaged within the coat protein shell of virus-like particles (VLPs) were studied to provide a comprehensive assessment of such factors. Such entrainment did not seem to perturb enzyme function, but it did significantly enhance enzyme stability against several denaturing stimuli such as heat, organic solvents, and chaotropic ...
Soumen Das, Liangjun Zhao, Kristen Elofson, M.G. Finn   +3 more
openaire   +2 more sources

Bioengineering virus‐like particles as vaccines

Biotechnology and Bioengineering, 2013
ABSTRACTVirus‐like particle (VLP) technology seeks to harness the optimally tuned immunostimulatory properties of natural viruses while omitting the infectious trait. VLPs that assemble from a single protein have been shown to be safe and highly efficacious in humans, and highly profitable.
Lua, Linda H. L., Connors, Natalie K., Sainsbury, Frank, Chuan, Yap P., Wibowo, Nani, Middelberg, Anton P. J.   +5 more
openaire   +3 more sources

Virus-like particles in Basidiobolus species

Mycopathologia, 1986
Transmission electron microscopy of ultrathin sections of hyphal cells of Basidiobolus haptosporus and B. ranarum revealed the presence of particulate inclusions consistent in morphology with that described in certain other fungi as virus-like particles.
R G, Garrison, A M, Fiskin
openaire   +2 more sources