Results 111 to 120 of about 722,631 (394)

Population dynamics of an RNA virus and its defective interfering particles in passage cultures [PDF]

, 2010
Background Viruses can fall prey to their defective interfering (DI) particles. When viruses are cultured by serial passage on susceptible host cells, the presence of virus-like DI particles can cause virus populations to rise and fall, reflecting ...
A Ives, A Mann, A Meyerhans, AC Marriott, AJ Bellett, AS Huang, B Dropulic, B Efron, CR Bangham, D Endy, D Garcin, E Szathmary, E Szathmary, EL Palma, G Wertz, GW Nelson, H Kim, J Aaskov, J Garcia-Arriaza, J Garcia-Arriaza, J Garcia-Arriaza, JJ Holland, JJ Holland, John Yin, JS Yount, KA Stauffer Thompson, Kristen A Stauffer Thompson, L Roux, L Roux, MH Malim, MJ Sekellick, MJ Sekellick, NJ DePolo, NJ Dimmock, P Arstila, P von Magnus, RA Lazzarini, S Noble, SA Frank, TB Kirkwood, W Henle, WJ Bean   +41 more
core   +3 more sources

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Identical Particles in Quantum Mechanics [PDF]

arXiv, 2009
If, in a system of identical particles, the one particle state is defined by the partial trace to one of the component spaces of the total Hilbert space, then all one particle states are identical. The particles are indistinguishable. This is often thought to be a typical quantum mechanical phenomenon. I will show however that an analogous procedure to
arxiv  

Stabilization of a Virus-Like Particle and Its Application as a Nanoreactor at Physiological Conditions

Biomacromolecules, 2017
Virus-like particles are very interesting tools for application in bionanotechnology, due to their monodisperse features and biocompatibility. In particular, the cowpea chlorotic mottle virus (CCMV) capsid has been studied extensively as it can be ...
Lise Schoonen, S. Maassen, R. Nolte, J. V. van Hest   +3 more
semanticscholar   +1 more source

Recombinant Hepatitis E Capsid Protein Self-Assembles into a Dual-Domain T = 1 Particle Presenting Native Virus Epitopes [PDF]

, 1999
The three-dimensional structure of a self-assembled, recombinant hepatitis E virus particle has been solved to 22-Å resolution by cryo-electron microscopy and three-dimensional image reconstruction.
Cheng, R.Holland, Hammar, Lena, Kato, Kenzo, Li, Tiancheng, Miyamura, Tatsuo, Takeda, Naokazu, Xing, Li   +6 more
core   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Virus-Like Particle Vaccination Protects Nonhuman Primates from Lethal Aerosol Exposure with Marburgvirus (VLP Vaccination Protects Macaques against Aerosol Challenges)

Viruses, 2016
Marburg virus (MARV) was the first filovirus to be identified following an outbreak of viral hemorrhagic fever disease in Marburg, Germany in 1967. Due to several factors inherent to filoviruses, they are considered a potential bioweapon that could be ...
John M. Dye, Kelly L. Warfield, Jay B. Wells, Robert C. Unfer, Sergey Shulenin, Hong Vu, Donald K. Nichols, M. Javad Aman, Sina Bavari   +8 more
doaj   +1 more source

Comparative Molecular Biology Approaches for the Production of Poliovirus Virus-Like Particles Using Pichia pastoris

mSphere, 2020
For enteroviruses such as poliovirus (PV), empty capsids, which are antigenically indistinguishable from mature virions, are produced naturally during viral infection.
Lee Sherry, Keith Grehan, Joseph S. Snowden, Michael L. Knight, Oluwapelumi O. Adeyemi, David J. Rowlands, Nicola J. Stonehouse   +6 more
doaj   +1 more source

Optimized Formulation of a Thermostable Spray-Dried Virus-Like Particle Vaccine against Human Papillomavirus.

Molecular Pharmaceutics, 2016
Existing vaccines against human papillomavirus (HPV) require continuous cold-chain storage. Previously, we developed a bacteriophage virus-like particle (VLP)-based vaccine for HPV infection, which elicits broadly neutralizing antibodies against diverse ...
Sugandha Saboo, Ebenezer Tumban, Julianne Peabody, D. Wafula, D. Peabody, B. Chackerian, Pavan Muttil   +6 more
semanticscholar   +1 more source

Structure-based engineering of papillomavirus major capsid L1: controlling particle assembly [PDF]

, 2007
The outer shell of the papillomavirus particle is comprised of 72 pentamers of the major capsid L1 protein arranged on a T = 7 icosahedral lattice. The recombinant L1 can form T = 7 virus-like particles in vitro.
Bishop, Brooke, Chen, Xiaojiang S, Dasgupta, Jhimli   +2 more
core   +3 more sources