Results 131 to 140 of about 722,631 (394)

A Selection for Assembly Reveals That a Single Amino Acid Mutant of the Bacteriophage MS2 Coat Protein Forms a Smaller Virus-like Particle.

open access: yesNano letters (Print), 2016
Virus-like particles are used to encapsulate drugs, imaging agents, enzymes, and other biologically active molecules in order to enhance their function. However, the size of most virus-like particles is inflexible, precluding the design of appropriately ...
Michael A. Asensio   +7 more
semanticscholar   +1 more source

Virus-like particle vaccines against BK and JC polyomaviruses [PDF]

open access: yes, 2018
Nearly all healthy adults are asymptomatically infected with human polyomaviruses. In immunosuppressed individuals, the infection can reactivate and cause disease.
Buck, Christopher B.   +3 more
core   +1 more source

Immunization of Swine with Virus-like Replicon Particles: Proof of Concept [PDF]

open access: yes, 2007
Pigs were inoculated with virus-like replicon particle (VRP) vaccines expressing the influenza hemagglutinin (HA) protein. A robust antibody response was present following the inoculation.
Crabtree, Brenda G.   +3 more
core   +3 more sources

Kidney Fibrosis In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses kidney diseases with a focus on kidney fibrosis and the models currently used. It highlights the limitations of animal and 2D in vitro models in replicating human kidney anatomy and physiology. Consequently, there is a significant need for humanized 3D in vitro models, such as 3D cell aggregates, membranes and hydrogels, on‐chip ...
Gabriele Addario   +2 more
wiley   +1 more source

An Underlying Asymmetry within Particle-size Segregation [PDF]

open access: yesarXiv, 2015
We experimentally study particle scale dynamics during segregation of a bidisperse mixture under oscillatory shear. Large and small particles show an underlying asymmetry that is dependent on the local particle concentration, with small particles segregating faster in regions of many large particles and large particles segregating slower in regions of ...
arxiv  

Virus like particle-based vaccines against emerging infectious disease viruses

open access: yesVirologica Sinica, 2016
Emerging infectious diseases are major threats to human health. Most severe viral disease outbreaks occur in developing regions where health conditions are poor. With increased international travel and business, the possibility of eventually transmitting
Jinliang Liu   +5 more
semanticscholar   +1 more source

Co‐Delivery of Multiple Toll‐Like Receptor Agonists and Avian Influenza Hemagglutinin on Protein Nanoparticles Enhances Vaccine Immunogenicity and Efficacy

open access: yesAdvanced Healthcare Materials, EarlyView.
This research highlights a novel application of protein nanoparticles to effectively modulate the strength, breadth, and bias of an immune response against influenza virus. Nanoparticles precisely co‐delivering antigen (H5) and multiple adjuvants (CpG and FliCc) present a way to improve and direct prophylactic immune responses which can be applicable ...
Aaron Ramirez   +6 more
wiley   +1 more source

Electromagnetic Radiation and Motion of Real Particle [PDF]

open access: yesarXiv, 2000
Relativistically covariant equation of motion for real dust particle under the action of electromagnetic radiation is derived. The particle is neutral in charge. Equation of motion is expressed in terms of particle's optical properties, standardly used in optics for stationary particles.
arxiv  

An Intranasal Virus-Like Particle Vaccine Broadly Protects Mice from Multiple Subtypes of Influenza A Virus

open access: yesmBio, 2015
Influenza virus infections are a global public health problem, with a significant impact of morbidity and mortality from both annual epidemics and pandemics.
L. M. Schwartzman   +5 more
semanticscholar   +1 more source

Influenza virus-like particle vaccines

open access: yesExpert Review of Vaccines, 2009
Enveloped virus-like particle (VLP) vaccines containing influenza hemagglutinin (HA) and neuraminidase (NA) antigens are produced easily in insect or mammalian cells via the simultaneous expression of HA and NA along with a viral core protein, such as influenza matrix (M1) or a retroviral Gag protein.
openaire   +2 more sources

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