Results 131 to 140 of about 722,631 (394)
Virus-like particles are used to encapsulate drugs, imaging agents, enzymes, and other biologically active molecules in order to enhance their function. However, the size of most virus-like particles is inflexible, precluding the design of appropriately ...
Michael A. Asensio+7 more
semanticscholar +1 more source
Virus-like particle vaccines against BK and JC polyomaviruses [PDF]
Nearly all healthy adults are asymptomatically infected with human polyomaviruses. In immunosuppressed individuals, the infection can reactivate and cause disease.
Buck, Christopher B.+3 more
core +1 more source
Immunization of Swine with Virus-like Replicon Particles: Proof of Concept [PDF]
Pigs were inoculated with virus-like replicon particle (VRP) vaccines expressing the influenza hemagglutinin (HA) protein. A robust antibody response was present following the inoculation.
Crabtree, Brenda G.+3 more
core +3 more sources
Kidney Fibrosis In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models
This review discusses kidney diseases with a focus on kidney fibrosis and the models currently used. It highlights the limitations of animal and 2D in vitro models in replicating human kidney anatomy and physiology. Consequently, there is a significant need for humanized 3D in vitro models, such as 3D cell aggregates, membranes and hydrogels, on‐chip ...
Gabriele Addario+2 more
wiley +1 more source
An Underlying Asymmetry within Particle-size Segregation [PDF]
We experimentally study particle scale dynamics during segregation of a bidisperse mixture under oscillatory shear. Large and small particles show an underlying asymmetry that is dependent on the local particle concentration, with small particles segregating faster in regions of many large particles and large particles segregating slower in regions of ...
arxiv
Virus like particle-based vaccines against emerging infectious disease viruses
Emerging infectious diseases are major threats to human health. Most severe viral disease outbreaks occur in developing regions where health conditions are poor. With increased international travel and business, the possibility of eventually transmitting
Jinliang Liu+5 more
semanticscholar +1 more source
This research highlights a novel application of protein nanoparticles to effectively modulate the strength, breadth, and bias of an immune response against influenza virus. Nanoparticles precisely co‐delivering antigen (H5) and multiple adjuvants (CpG and FliCc) present a way to improve and direct prophylactic immune responses which can be applicable ...
Aaron Ramirez+6 more
wiley +1 more source
Electromagnetic Radiation and Motion of Real Particle [PDF]
Relativistically covariant equation of motion for real dust particle under the action of electromagnetic radiation is derived. The particle is neutral in charge. Equation of motion is expressed in terms of particle's optical properties, standardly used in optics for stationary particles.
arxiv
Influenza virus infections are a global public health problem, with a significant impact of morbidity and mortality from both annual epidemics and pandemics.
L. M. Schwartzman+5 more
semanticscholar +1 more source
Influenza virus-like particle vaccines
Enveloped virus-like particle (VLP) vaccines containing influenza hemagglutinin (HA) and neuraminidase (NA) antigens are produced easily in insect or mammalian cells via the simultaneous expression of HA and NA along with a viral core protein, such as influenza matrix (M1) or a retroviral Gag protein.
openaire +2 more sources