Results 151 to 160 of about 722,631 (394)
Journal of Virology, 2015 The molecular interaction between viral RNA and the cytosolic sensor RIG-I represents the initial trigger in the development of an effective immune response against infection with RNA viruses, resulting in innate immune activation and subsequent ...
V. Beljanski +9 more
semanticscholar +1 more source
Biophysical analysis of HTLV-1 particles reveals novel insights into particle morphology and Gag stoichiometry [PDF]
, 2010 Background Human T-lymphotropic virus type 1 (HTLV-1) is an important human retrovirus that is a cause of adult T-cell leukemia/lymphoma. While an important human pathogen, the details regarding virus replication cycle, including the nature of HTLV-1 ...
Chen, Yan +8 more
core +3 more sources
Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics
Advanced Healthcare Materials, EarlyView.This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold +2 more
wiley +1 more source
A Viral Platform for Chemical Modification and Multivalent Display
Journal of Nanobiotechnology, 2003 The ability to chemically modify the surfaces of viruses and virus-like particles makes it possible to confer properties that make them potentially useful in biotechnology, nanotechnology and molecular electronics applications. RNA phages (e.g. MS2) have
Peabody David S
doaj +1 more source
Enveloped virus-like particle platforms: vaccines of the future?
Expert Review of Vaccines, 2015 The techniques to produce effective vaccines have evolved, and the early vaccines (live, inactivated, subunit…) are no longer considered as the most appropriate for new vaccine development.
F. Pitoiset, T. Vazquez, B. Bellier
semanticscholar +1 more source
Metal–Organic Framework‐Based Antimicrobial Touch Surfaces to Prevent Cross‐Contamination
Advanced Materials, EarlyView.A MOF‐based antimicrobial door handle cover is developed. It completely inhibits the cross‐contamination of Gram‐positive bacterial species (Staphylococcus aureus, and Enterococcus faecalis), Gram‐negative bacterial species (Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii), and fungi (Candida albicans). Abstract Infection diseases
Javier Fonseca +8 more
wiley +1 more source
Emerging Microbes and Infections, 2014 In light of the current outbreak of Ebola virus disease, there is an urgent need to develop effective therapeutics to treat Ebola infection, and drug repurposing screening is a potentially rapid approach for identifying such therapeutics.
Jennifer Kouznetsova +10 more
semanticscholar +1 more source
Chikungunya virus-like particle vaccine [PDF]
, 2013 Chikungunya virus (CHIKV) is an arthropod-borne alphavirus (family Togaviridae) and is the causative agent of chikungunya fever. This disease is characterised by the sudden onset of high fever and long-lasting arthritic disease.
Metz, S.W.H.
core +1 more source
Functional analysis of the Bunyamwera orthobunyavirus Gc glycoprotein [PDF]
, 2009 The virion glycoproteins Gn and Gc of Bunyamwera orthobunyavirus (family Bunyaviridae) are encoded by the M RNA genome segment and have roles in both viral attachment and membrane fusion.
Brauburger, K. +4 more
core +2 more sources
Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting
Advanced Materials, EarlyView.CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu +4 more
wiley +1 more source