Results 121 to 130 of about 4,892,090 (362)

Accelerating the Tempo of the Segmentation Clock by Reducing the Number of Introns in the Hes7 Gene

open access: yesCell Reports, 2013
Periodic somite segmentation is controlled by the cyclic gene Hes7, whose oscillatory expression depends upon negative feedback with a delayed timing.
Yukiko Harima   +4 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Roles of the membrane-reentrant β-hairpin-like loop of RseP protease in selective substrate cleavage

open access: yeseLife, 2015
Molecular mechanisms underlying substrate recognition and cleavage by Escherichia coli RseP, which belongs to S2P family of intramembrane-cleaving proteases, remain unclear.
Koichiro Akiyama   +5 more
doaj   +1 more source

PRRSV, the virus

open access: yesVeterinary Research, 2000
Porcine reproductive and respiratory syndrome virus (PRRSV) is a positive-strand RNA virus that belongs to the Arteriviridae family. PRRSV grows in primary alveolar macrophages and in monkey kidney cell lines. The genomic RNA is approximately 15 kb.
openaire   +4 more sources

Influenza virus

open access: yesMedicina, 2007
Every year, especially during the cold season, many people catch an acute respiratory disease, namely flu. It is easy to catch this disease; therefore, it spreads very rapidly and often becomes an epidemic or a global pandemic. Airway inflammation and other body ailments, which form in a very short period, torment the patient several weeks. After that,
Juozapaitis, Mindaugas   +1 more
openaire   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Evaluation of Artificial Intelligence-generated Responses to Common Plastic Surgery Questions

open access: yesPlastic and Reconstructive Surgery, Global Open, 2023
Hinpetch Daungsupawong, PhD   +1 more
doaj   +1 more source

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