Results 101 to 110 of about 4,225,102 (309)
, 2009 Pepino mosaic virus (PepMV) is a relatively new plant virus that has become a signifi cant agronomical problem in a relatively short period of time.
Vlugt, R.A.A., van der
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Viruses infecting carnations and dianthus species in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Horticultural Science at Massey University [PDF]
, 1975 Five viruses were detected in commercial carnations and these and a further four occurred in Dianthus species from gardens. Carnation mottle virus (CarMV) and carnation etched ring virus (CERV-50) were widespread in commercial carnations; arabis mosaic ...
Bennett, Peter Roger
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Evaluation of Artificial Intelligence-generated Responses to Common Plastic Surgery Questions
Plastic and Reconstructive Surgery, Global Open, 2023 Hinpetch Daungsupawong, PhD +1 more
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Enfermedades Infecciosas y Microbiología Clínica, 2007 Probablemente esta misma estrategia fue la que ayudo a controlar con eficacia el brote del sindrome respiratorio grave y agudo (SARS) que tanto alarmo a la comunidad internacional durante la primavera del 20033. Este brote sin precedentes demostro la eficacia con la que la comunidad cientifica pudo identificar un nuevo patogeno, proponer metodos de ...
openaire +1 more source
Clinics in Laboratory Medicine, 2017 For chikungunya virus (CHIKV), the long-term sequelae from infection are yet ill-defined. The prolonged debilitating arthralgia associated with CHIKV infection has tremendous potential for impacting the global economy and should be considered when evaluating the human burden of disease and the allocation of resources.
Vu, David M. +2 more
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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The potential of H5N1 viruses to adapt to bovine cells varies throughout evolution
Nature CommunicationsAvian influenza H5N1 clade 2.3.4.4b viruses caused a global panzootic and, unexpectedly, widespread outbreaks in dairy cattle, therefore representing a pandemic threat.
Matthew L. Turnbull +32 more
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