Results 141 to 150 of about 5,701,493 (405)

The Aedes aegypti Domino Ortholog p400 Regulates Antiviral Exogenous Small Interfering RNA Pathway Activity and ago-2 Expression

mSphere, 2020
Arboviruses are pathogens of humans and animals. A better understanding of the interactions between these pathogens and the arthropod vectors, such as mosquitoes, that transmit them is necessary to develop novel control measures.
Melanie McFarlane, Floriane Almire, Joy Kean, Claire L. Donald, Alma McDonald, Bryan Wee, Mathilde Lauréti, Margus Varjak, Sandra Terry, Marie Vazeille, Rommel J. Gestuveo, Isabelle Dietrich, Colin Loney, Anna-Bella Failloux, Esther Schnettler, Emilie Pondeville, Alain Kohl   +16 more
doaj   +1 more source

Viable porcine arteriviruses with deletions proximal to the 3 ' end of the genome [PDF]

, 2001
In order to obtain attenuated live vaccine candidates of porcine reproductive and respiratory syndrome virus (PRRSV), a series of deletions was introduced at the 3′ end of the viral genome using an infectious cDNA clone of the Lelystad virus isolate. RNA
Kroese, M.V., Meulenberg, J.J.M., Rottier, P.J.M., Verheije, M.H.   +3 more
core   +2 more sources

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

Journal of Virology, 1994
Virologic and immunologic studies were performed on five patients presenting with primary human immunodeficiency virus type 1 (HIV-1) infection. CD8+ cytotoxic T lymphocyte (CTL) precursors specific for cells expressing antigens of HIV-1 Gag, Pol, and ...
R. Koup, J. Safrit, Yun-zhen Cao, C. Andrews, G. McLeod, W. Borkowsky, C. Farthing, D. Ho   +7 more
semanticscholar   +1 more source

Influenza virus: The biology of a changing virus

, 2008
Influenza viruses are members of the family Orthomyxoviridae and include influenza virus types A, B, and C. This introduction provides an overview of influenza virus classification, structure, and life cycle. We also include a brief review of the clinical manifestations of influenza and the molecular determinants for virulence. The genetic diversity of
Samira Mubareka, Samira Mubareka, Peter Palese   +2 more
openaire   +2 more sources

Altruism in a virus

Nature Microbiology, 2019
A recent study finds that viruses cooperate altruistically to overcome innate host immunity and that this can be explained in the same way we explain altruism between animals.
Leeks, A, West, S
openaire   +3 more sources

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

Molecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen, Saurav Subedi, Federico La Manna, Sofia Jarrin, Irida Papapostolou, Marianna Kruithof‐de Julio, Christine Peinelt   +6 more
wiley   +1 more source

NSm is a critical determinant for bunyavirus transmission between vertebrate and mosquito hosts

Nature Communications
Bunyavirales is a very large order including viruses infecting a variety of taxonomic groups such as arthropods, vertebrates, plants, and protozoa. Some bunyaviruses are transmitted between vertebrate hosts by blood-sucking arthropods and cause major ...
Selim Terhzaz, David Kerrigan, Floriane Almire, Agnieszka M. Szemiel, Joseph Hughes, Jean-Philippe Parvy, Massimo Palmarini, Alain Kohl, Xiaohong Shi, Emilie Pondeville   +9 more
doaj   +1 more source

How do Viruses Attack Anti-Virus Programs [PDF]

Umakant Mishra, "How do Viruses Attack Anti-virus Programs", TRIZsite Journal, June 2012, http://trizsite.tk/trizsite/articles/default.asp?month=Jun&year=2012, 2013
As the anti-viruses run in a trusted kernel level any loophole in the anti-virus program can enable attackers to take full control over the computer system and steal data or do serious damages. Hence the anti-virus engines must be developed with proper security in mind.
arxiv  

DNA Confinement drives uncoating of the HIV Virus [PDF]

, 2014
We present a model for the uncoating of the HIV virus driven by forces exerted on the protein shell of HIV generated by DNA confinement.
arxiv   +1 more source

ICTV Virus Taxonomy Profile: Flaviviridae

Journal of General Virology, 2017
The Flaviviridae is a family of small enveloped viruses with RNA genomes of 9000–13 000 bases. Most infect mammals and birds. Many flaviviruses are host-specific and pathogenic, such as hepatitis C virus in the genus Hepacivirus.
P. Simmonds, P. Becher, J. Bukh, E. Gould, G. Meyers, T. Monath, Scott Muerhoff, A. Pletnev, Rebecca R Rico-Hesse, Donald B. Smith, J. Stapleton   +10 more
semanticscholar   +1 more source