Results 161 to 170 of about 1,680,012 (219)

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Arbovirus surveillance and bloodmeal analysis in mosquito species from Northern Kenya

Akengo HA, Mutisya J, Mulwa FM, Chelangat B, Koka H, Chepkorir E, Langat S, Lutomiah J, Mukhaye E, Nyamota R, Akoko JM, Mitzel D, Wilson W, Nyanjom SG, Bett B, Abkallo HM.   +15 more
europepmc   +1 more source

Evaluation and comparison of three qPCR commercial assays and three automated platforms for the detection of monkeypox virus DNA. [PDF]

Microbiol Spectr
Usal M, Andréani J, Truffot A, Chevalier C, Larrat S, Lupo J, Morand P, Ferraris O, Germi R.   +8 more
europepmc   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Editorial for Special Issue "Molecular Research in Vaccinology and Vaccine Development". [PDF]

Curr Issues Mol Biol
Farsang A.
europepmc   +1 more source

Expanding diversity of tick-borne phleboviruses (Phlebovirus mukawaense, Mudanjiang phlebovirus, Gomselga Virus, and Onega tick phlebovirus) in Russia. [PDF]

PLoS One
Kartashov MY, Kurushina VY, Yanshin AO, Zheleznova AS, Svirin KA, Tregubchak TV, Ternovoi VA, Agafonov AP, Gladysheva AV.   +8 more
europepmc   +1 more source

Pairwise Respiratory Viral Co-Detection Patterns Before, During, and After the COVID-19 Pandemic: An 18-Year Multiplex PCR Surveillance Study. [PDF]

Microorganisms
Jung BK, Han JS, Kim JK.
europepmc   +1 more source

Partial pupil-sparing third nerve palsy as a manifestation of cerebral toxoplasmosis in an HIV-positive patient: A case report. [PDF]

Am J Ophthalmol Case Rep
Aljohani HA, Alzahrani AS, Alrashid AS, Tuwair I.   +3 more
europepmc   +1 more source

TIM-1 promotes infection with mosquito cell-derived alphaviruses through virion-associated phospholipids. [PDF]

Emerg Microbes Infect
Yoo JE, de Bruin ACM, Reßin H, Paužuolis M, Liu L, Moosmann A, Becker M, Lasswitz L, Groß R, Gerold G.   +9 more
europepmc   +1 more source

Modeled Scenario Projections for the Ebola Disease Outbreak Caused by Bundibugyo Virus, 2026. [PDF]

MMWR Morb Mortal Wkly Rep
Mooring EQ, Koval WT, Routledge I, Holmdahl I, Hudson K, España G, Kahn R, Bruce BB.   +7 more
europepmc   +1 more source