Results 161 to 170 of about 5,701,493 (405)
Zika virus impairs growth in human neurospheres and brain organoids
Science, 2016 Zika virus tested in human brain organoids The pernicious and resilient Aedes mosquito is rapidly spreading Zika virus (ZIKV) through the Americas. ZIKV infection mostly causes mild disease, but in some patients, nervous system involvement is indicated ...
P. Garcez +9 more
semanticscholar +1 more source
Emerging Infectious Diseases, 2013 This is a lucid read on a complex virus, cytomegalovirus (CMV), that affects those in all ages of life from the unborn fetus to the elderly pensioner. Griffiths has used one of the many self-publishing, internet-based services to publish and distribute this book via the popular amazon.com and amazon.co.uk websites.
openaire +3 more sources
Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan +6 more
wiley +1 more source
Evolution of Computer Virus Concealment and Anti-Virus Techniques: A Short Survey [PDF]
International Journal of Computer Science Issues (IJCSI), Vol. 8,
No. 1, 2011, pp. 113-121, 2011 This paper presents a general overview on evolution of concealment methods in computer viruses and defensive techniques employed by anti-virus products. In order to stay far from the anti-virus scanners, computer viruses gradually improve their codes to make them invisible.
arxiv
First report of autochthonous transmission of Zika virus in Brazil
Memórias do Instituto Oswaldo Cruz, 2015 In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil.
C. Zanluca +5 more
semanticscholar +1 more source
Virology, 2015 Viral diagnosis and discovery are receiving increasing emphasis with the recognition of their importance in addressing the challenges of emerging infectious and chronic diseases, and the advent of antiviral drugs with which to reduce the morbidity and mortality of viral infections.
Lipkin, W. Ian, Anthony, Simon J.
openaire +2 more sources
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Accelerating the Tempo of the Segmentation Clock by Reducing the Number of Introns in the Hes7 Gene
Cell Reports, 2013 Periodic somite segmentation is controlled by the cyclic gene Hes7, whose oscillatory expression depends upon negative feedback with a delayed timing.
Yukiko Harima +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source