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Essential facts Zika virus disease is caused by a virus that is transmitted by the Aedes mosquito. While it generally causes a mild illness, there is increasing concern that it is harmful in pregnancy and can cause congenital abnormalities in infants born to women infected with the virus.
Lyle R, Petersen +3 more
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A number of viruses can initiate central nervous system (CNS) diseases that include demyelination as a major feature of neuropathology. In humans, the most prominent demyelinating diseases are progressive multifocal leukoencephalopathy, caused by JC papovirus destruction of oligodendrocytes, and subacute sclerosing panencephalitis, an invariably fatal ...
Fazakerley, JK, Walker, R
openaire +4 more sources
Virus-Vectored Influenza Virus Vaccines [PDF]
Despite the availability of an inactivated vaccine that has been licensed for >50 years, the influenza virus continues to cause morbidity and mortality worldwide. Constant evolution of circulating influenza virus strains and the emergence of new strains diminishes the effectiveness of annual vaccines that rely on a match with circulating influenza ...
Ralph Tripp, S. Tompkins
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The International Virus Bioinformatics Meeting 2020
The International Virus Bioinformatics Meeting 2020 was originally planned to take place in Bern, Switzerland, in March 2020. However, the COVID-19 pandemic put a spoke in the wheel of almost all conferences to be held in 2020.
Franziska Hufsky +18 more
doaj +1 more source
Experiences of diagnosis, stigma, culpability, and disclosure in male patients with hepatitis C virus: an interpretative phenomenological analysis [PDF]
The current study aimed to explore the lived experience of patients with hepatitis C virus infection. Semi-structured interviews were conducted with seven male participants living with hepatitis C virus and were analysed using interpretative ...
Adele Dickson +11 more
core +3 more sources
Some strains of the inherited bacterium Wolbachia have been shown to be effective at reducing the transmission of dengue virus (DENV) and other RNA viruses by Aedes aegypti in both laboratory and field settings and are being deployed for DENV control ...
Stephanie M. Rainey +9 more
doaj +1 more source
EMERGING VIRUSES ARE AN UNDERESTIMATED CAUSE OF UNDIAGNOSED FEBRILE ILLNESS IN UGANDA
Intro: Viruses that cause acute febrile illness (AFI) in sub-Saharan Africa (SSA) lead to a spectrum of clinical disease from mild to life-threatening. Viral infection is often undiagnosed, resulting in onward transmission of high consequence pathogens ...
S. Ashraf +18 more
doaj +1 more source
Background Following the West Africa Ebola virus disease (EVD) outbreak (2013–2016), WHO developed a preparedness checklist for its member states. This checklist is currently being applied for the first time on a large and systematic scale to prepare for
Olushayo Oluseun Olu +11 more
doaj +1 more source
The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. [PDF]
Following intracerebral inoculation of adult Balb/c Byj mice, the MHV-4 strain of mouse hepatitis virus (MHV) had an LD50 of less than 0.1 PFU, whereas its monoclonal antibody resistant variant V5A13.1 had an LD50 of 10(4.2) PFU.
Bloom, F +3 more
core +1 more source

