Results 31 to 40 of about 2,705,124 (318)

Influenza Virus [PDF]

Trends in Microbiology, 2018
This infographic briefly summarises the natural history, replication cycle, and pathogenesis of influenza viruses, the cause of seasonal influenza and of influenza pandemics. Influenza viruses infect many vertebrates, with Influenza A, B and C viruses (IAV, IBV, and ICV) infecting humans. High mutation rates allow the evasion of immunity.
openaire   +3 more sources

Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]

, 2014
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Dove, Brian K., Geoff Pearson, Kathryn A Ryan, Newman, Edmund, Wendy S Barclay, Bean, Thomas J., Carroll, Miles W., Miles W Carroll, Brian K Dove, Bassam Hallis, Edmund Newman, Easton, A. J. (Andrew J.), Marriott, Anthony C., Hallis, Bassam, Whittaker, Catherine J., Dimmock, N. J., Stuart Dowall, Silman, Nigel J., Barclay, Wendy S., Rayner, Emma, Bruce, Christine, Taylor, Irene, Jenna Plank, Andrew J Easton, Pearson, Geoff, Catherine J Whittaker, Nigel J Silman, Christine Bruce, Ryan, Kathryn A., Nigel J Dimmock, Irene Taylor, Emma Rayner, Plank, Jenna, Anthony C Marriott, Dowall, Stuart, Thomas J Bean   +35 more
core   +1 more source

Influenza A Virus: Host–Virus Relationships [PDF]

Viruses, 2020
We are in the midst of a pandemic where the infective agent has been identified, but how it causes mild disease in some and fatally severe disease in other infected individuals remains a mystery [...]
openaire   +3 more sources

Tomato chocolàte virus: a new plant virus infecting tomato and a proposed member of the genus Torradovirus [PDF]

, 2010
A new virus was isolated from a tomato plant from Guatemala showing necrotic spots on the bases of the leaves and chocolate-brown patches on the fruits.
Verbeek, M., Dullemans, A.M., Heuvel, J.F.J.M., van den, Paul Maris, van den Heuvel, J.F.J.M., Maris, P.C., Vlugt, R.A.A., van der, Hans van den Heuvel, Martin Verbeek, Annette Dullemans, René van der Vlugt, van der Vlugt, R.A.A.   +11 more
core   +1 more source

A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]

, 2011
Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn, Nicole L. Edworthy, Andrew J. Easton, Meng, Bo, Easton, A. J. (Andrew J.), Bo Meng, Scott, P. D. (Paul D.), Marriott, Anthony C., Anthony C. Marriott, Nigel J. Dimmock, Dimmock, N. J., Paul D. Scott   +11 more
core   +1 more source

Career development for infection and immunity research in Uganda: a decade of experience from the Makerere University – Uganda Virus Research Institute research and training programme [version 1; peer review: 2 approved]

AAS Open Research, 2020
Background: The Makerere University/Uganda Virus Research Institute (UVRI) Centre of Excellence for Infection & Immunity Research and Training (MUII) is a collaborative programme supporting excellence in Infection and Immunity (I&I) research in Uganda ...
Damalie Nakanjako, Flavia Zalwango, Pamela Wairagala, Fiona Luboga, Irene Andia Biraro, Victoria Diana Bukirwa, Mary Gorrethy Mboowa, Steve Cose, Janet Seeley, Alison Elliott   +9 more
doaj   +1 more source

Junín Virus Pathogenesis and Virus Replication [PDF]

Viruses, 2012
Junín virus, the etiological agent of Argentine hemorrhagic fever, causes significant morbidity and mortality. The virus is spread through the aerosolization of host rodent excreta and endemic to the humid pampas of Argentina. Recently, significant progress has been achieved with the development of new technologies (e.g.
Olga Kolokoltsova, Allan Brasier, Slobodan Paessler, Clarence Peters, Cheng Huang, Alexey Seregin, Ashley Grant   +6 more
openaire   +3 more sources

Inhibitors of the interferon response enhance virus replication in vitro. [PDF]

, 2014
This work was supported by the University of St Andrews (CSA, CES) and the Wellcome Trust (grant 087751/A/08/Z) (RER).Virus replication efficiency is influenced by two conflicting factors, kinetics of the cellular interferon (IFN) response and induction ...
Richard E. Randall, Catherine S. Adamson, Catherine S Adamson, Claire E Stewart, Richard E Randall, Adamson, Catherine S, Stewart, Claire Emma, Randall, Richard Edward, Claire E. Stewart   +8 more
core   +1 more source

Whole-genome sequence analysis reveals the circulation of multiple SARS-CoV-2 variants of concern in Nairobi and neighboring counties, Kenya between March and July 2021

Virology Journal, 2022
The emergence and rapid spread of SARS-CoV-2 variants of concern (VOC) have been linked to new waves of COVID-19 epidemics occurring in different regions of the world.
Samoel Ashimosi Khamadi, Silvanos Opanda, Samwel Lifumo Symekher, Samson Konongoi Limbaso, Solomon Langat, Josyline Kaburi Cirindi, Milkah Mwangi, Nicholas Mwikwabe, Seth Okeyo, Edith Koskei, James Mutisya, Samwel Owaka, Albert Nyunja, Hellen Koka, Meshack Wadegu, Esther Chitechi, Rachel Achilla, Janet Masitsa Majanja, Lucy Kanyara, Evans Amukoye, Wallace Bulimo   +20 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source