Results 31 to 40 of about 4,225,102 (309)

Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain [PDF]

, 2012
Segment 7 of influenza A virus produces up to four mRNAs. Unspliced transcripts encode M1, spliced mRNA2 encodes the M2 ion channel, while protein products from spliced mRNAs 3 and 4 have not previously been identified.
Digard, Paul, Firth, Andrew E., Fodor, Ervin, Gog, Julia R., Hutchinson, Edward C., Jagger, Brett W., Kang, Zi H., Kash, John C., Robb, Nicole, Schwartzman, Louis M., Stuart, Amanda D., Taubenberger, Jeffery K., Wise, Helen M.   +12 more
core   +4 more sources

Memory B cells and CD8⁺ lymphocytes do not control seasonal influenza A virus replication after homologous re-challenge of rhesus macaques. [PDF]

, 2011
This study sought to define the role of memory lymphocytes in the protection from homologous influenza A virus re-challenge in rhesus macaques. Depleting monoclonal antibodies (mAb) were administered to the animals prior to their second experimental ...
Carroll, Timothy D, Fritts, Linda, Matzinger, Shannon R, McChesney, Michael B, Miller, Christopher J   +4 more
core   +3 more sources

Hendra Virus [PDF]

Veterinary Clinics of North America: Equine Practice, 2014
Hendra virus infection of horses occurred sporadically between 1994 and 2010 as a result of spill-over from the viral reservoir in Australian mainland flying-foxes, and occasional onward transmission to people also followed from exposure to affected horses.
openaire   +2 more sources

Long-lasting cross-protection against influenza A by neuraminidase and M2e-based immunization strategies [PDF]

, 2016
There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here, we compared protection and CD8+ T cell responses following challenge with H1N1 2009 pandemic and
Callewaert, Nico, Fiers, Walter, Saelens, Xavier, Schepens, Bert, Schotsaert, Michael, Smet, Anouk, Stegalkina, Svetlana, Vanderschaeghe, Dieter, Vogel, Thorsten U, Ysenbaert, Tine   +9 more
core   +2 more sources

Complete Genome Sequence of Diaphorina citri-associated C virus, a Novel Putative RNA Virus of the Asian Citrus Psyllid, Diaphorina citri. [PDF]

, 2016
We present here the complete nucleotide sequence and genome organization of a novel putative RNA virus identified in field populations of the Asian citrus psyllid, Diaphorina citri, through sequencing of the transcriptome followed by reverse ...
Falk, Bryce W, Nouri, Shahideh, Salem, Nidà   +2 more
core   +1 more source

Career development for infection and immunity research in Uganda: a decade of experience from the Makerere University – Uganda Virus Research Institute research and training programme [version 1; peer review: 2 approved]

AAS Open Research, 2020
Background: The Makerere University/Uganda Virus Research Institute (UVRI) Centre of Excellence for Infection & Immunity Research and Training (MUII) is a collaborative programme supporting excellence in Infection and Immunity (I&I) research in Uganda ...
Damalie Nakanjako, Flavia Zalwango, Pamela Wairagala, Fiona Luboga, Irene Andia Biraro, Victoria Diana Bukirwa, Mary Gorrethy Mboowa, Steve Cose, Janet Seeley, Alison Elliott   +9 more
doaj   +1 more source

Whole-genome sequence analysis reveals the circulation of multiple SARS-CoV-2 variants of concern in Nairobi and neighboring counties, Kenya between March and July 2021

Virology Journal, 2022
The emergence and rapid spread of SARS-CoV-2 variants of concern (VOC) have been linked to new waves of COVID-19 epidemics occurring in different regions of the world.
Samoel Ashimosi Khamadi, Silvanos Opanda, Samwel Lifumo Symekher, Samson Konongoi Limbaso, Solomon Langat, Josyline Kaburi Cirindi, Milkah Mwangi, Nicholas Mwikwabe, Seth Okeyo, Edith Koskei, James Mutisya, Samwel Owaka, Albert Nyunja, Hellen Koka, Meshack Wadegu, Esther Chitechi, Rachel Achilla, Janet Masitsa Majanja, Lucy Kanyara, Evans Amukoye, Wallace Bulimo   +20 more
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Molecular characterization of mumps viruses from the 2022–2023 outbreak reveals circulation of multiple genotypes in Uganda

Virology Journal
Mumps is a highly contagious viral disease caused by the mumps virus (MuV), a member of the genus Orthorubulavirus in the family Paramyxoviridae. Although effective vaccines exist, mumps vaccination is not yet part of Uganda’s routine immunization ...
Phionah Tushabe, Irene Turyahabwe, Henry Bukenya, James Peter Eliku, Francis Aine, Joseph Gaizi, Mary Nyachwo, Molly Birungi, Mayi Tibanagwa, Rena Patricia Nakyeyune, Prossy Namuwulya, Mary Bridget Nanteza, Josephine Bwogi   +12 more
doaj   +1 more source

Viable porcine arteriviruses with deletions proximal to the 3 ' end of the genome [PDF]

, 2001
In order to obtain attenuated live vaccine candidates of porcine reproductive and respiratory syndrome virus (PRRSV), a series of deletions was introduced at the 3′ end of the viral genome using an infectious cDNA clone of the Lelystad virus isolate. RNA
Kroese, M.V., Meulenberg, J.J.M., Rottier, P.J.M., Verheije, M.H.   +3 more
core   +2 more sources