Results 281 to 290 of about 4,892,090 (362)

Cortical Response to Acute Implantation of the Utah Optrode Array in Macaque Cortex

open access: yesAdvanced Healthcare Materials, EarlyView.
Delivering light deep into the brain over a large volume while causing minimal tissue damage is a major challenge for non‐human primate optogenetics. This study evaluates Utah Optrode Array designs in vivo, revealing how changes in shank geometry, surface texture, and insertion parameters minimize acute damage—offering a path toward high‐precision ...
Adrián Villamarin‐Ortiz   +8 more
wiley   +1 more source

Foot-and-mouth disease vaccine with insertion of a 24-amino acid VP1 G-H loop epitope of the Cathay virus provides broad antigenic coverage. [PDF]

open access: yesAppl Microbiol Biotechnol
Zhang K   +20 more
europepmc   +1 more source

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

open access: yesAdvanced Healthcare Materials, EarlyView.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark   +9 more
wiley   +1 more source

Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang   +6 more
wiley   +1 more source

Graphene‐Enhanced Plasmonic Interfaces: A General Strategy for Highly Sensitive Detection of Biomolecular Interactions

open access: yesAdvanced Healthcare Materials, EarlyView.
Monolayer graphene coating significantly enhances the sensing performance of conventional SPR biosensors. Its impact is evaluated using biologically relevant models, including antibody‐virus and peptide‐cell interactions. Graphene‐enhanced SPR enabled specific virus detection via antibodies and effective cell type discrimination using synthetic ...
Ahmar Hasnain   +7 more
wiley   +1 more source

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