Living Together Apart: Quantitative Perspectives on the Costs and Benefits of a Multipartite Genome Organization in Viruses. [PDF]
Johnson ML+5 more
europepmc +1 more source
Cortical Response to Acute Implantation of the Utah Optrode Array in Macaque Cortex
Delivering light deep into the brain over a large volume while causing minimal tissue damage is a major challenge for non‐human primate optogenetics. This study evaluates Utah Optrode Array designs in vivo, revealing how changes in shank geometry, surface texture, and insertion parameters minimize acute damage—offering a path toward high‐precision ...
Adrián Villamarin‐Ortiz+8 more
wiley +1 more source
Foot-and-mouth disease vaccine with insertion of a 24-amino acid VP1 G-H loop epitope of the Cathay virus provides broad antigenic coverage. [PDF]
Zhang K+20 more
europepmc +1 more source
Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark+9 more
wiley +1 more source
Human platelets support Semliki Forest virus replication. [PDF]
Stockwell CJ, Hindle MS.
europepmc +1 more source
Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang+6 more
wiley +1 more source
The Effect of Treating the Virus of Tobacco Mosaic With the Juices of Various Plants
B. M. Duggar, Joanne K. Armstrong
openalex +2 more sources
Monolayer graphene coating significantly enhances the sensing performance of conventional SPR biosensors. Its impact is evaluated using biologically relevant models, including antibody‐virus and peptide‐cell interactions. Graphene‐enhanced SPR enabled specific virus detection via antibodies and effective cell type discrimination using synthetic ...
Ahmar Hasnain+7 more
wiley +1 more source
From monolayer to spheroid: assessing influenza a virus infection in 2D and 3D cell culture of A549 and HEK293. [PDF]
Shokouhi H+4 more
europepmc +1 more source