Results 61 to 70 of about 3,262,736 (331)
ASFV pE146L-induced ER remodeling is essential for viral replication
Journal of VirologyAfrican swine fever virus (ASFV) causes a severe hemorrhagic disease, posing a significant threat to the global pig industry. Although the ASFV encodes nearly 200 proteins, the functions of many remain unknown.
Yilin Guo +12 more
doaj +1 more source
Sindbis virus ts103 has a mutation in glycoprotein E2 that leads to defective assembly of virions [PDF]
, 1989 Sindbis virus mutant ts103 is aberrant in the assembly of virus particles. During virus budding, proper nucleocapsid-glycoprotein interactions fail to occur such that particles containing many nucleocapsids are formed, and the final yield of virus is low.
Hahn, Chang S. +4 more
core
Self-assembly of model proteins into virus capsids
, 2017 We consider self-assembly of proteins into a virus capsid by the methods of molecular dynamics. The capsid corresponds either to SPMV or CCMV and is studied with and without the RNA molecule inside.
Cieplak, Marek, Wolek, Karol
core +1 more source
Stochastic dynamics of virus capsid formation: direct versus hierarchical self-assembly [PDF]
, 2012 Background: In order to replicate within their cellular host, many viruses have developed self-assembly strategies for their capsids which are sufficiently robust as to be reconstituted in vitro. Mathematical models for virus self-assembly usually assume
Baschek, Johanna E. +2 more
core +1 more source
Influenza A Virus Cell Entry, Replication, Virion Assembly and Movement
Frontiers in Immunology, 2018 Influenza viruses replicate within the nucleus of the host cell. This uncommon RNA virus trait provides influenza with the advantage of access to the nuclear machinery during replication.
D. Dou +4 more
semanticscholar +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
mBio, 2017 Alphaviruses are members of a group of small enveloped RNA viruses that includes important human pathogens such as Chikungunya virus and the equine encephalitis viruses.
Emily A. Byrd, Margaret Kielian
doaj +1 more source
Y-Box Binding Protein 1 Interacts with Dengue Virus Nucleocapsid and Mediates Viral Assembly
mBio, 2022 Infection with dengue virus (DENV) induces vast rearrangements of the endoplasmic reticulum, which allows the compartmentalization of viral RNA replication and particle assembly. Both processes occur in concert with viral and cellular proteins.
Mayra Diosa-Toro +5 more
doaj +1 more source
Role of dynamic capsomere supply for viral capsid self-assembly
, 2015 Many viruses rely on the self-assembly of their capsids to protect and transport their genomic material. For many viral systems, in particular for human viruses like hepatitis B, adeno or human immunodeficiency virus, that lead to persistent infections ...
Boettcher, Marvin A. +2 more
core +1 more source
RNA Control of HIV-1 Particle Size Polydispersity [PDF]
, 2014 HIV-1, an enveloped RNA virus, produces viral particles that are known to be much more heterogeneous in size than is typical of non-enveloped viruses. We present here a novel strategy to study HIV-1 Viral Like Particles (VLP) assembly by measuring the ...
Beck, Yvonne +9 more
core +7 more sources