Results 71 to 80 of about 2,295,443 (384)

Streamlining standard bacteriophage methods for higher throughput

open access: yesMethodsX, 2018
A universal tool in the culture-based study of bacterial viruses (bacteriophages, or phages) is the agar overlay, which is used in the isolation of new viruses, and in their quantification and purification.
Kathryn M. Kauffman, Martin F. Polz
doaj   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

open access: yesAdvanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li   +19 more
wiley   +1 more source

Isolation of infectious bronchitis virus from broiler [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2007
Infectious bronchitis virus (IBV) was isolated from broilers chicks. The virus isolation done by samples inoculation in chicken egg embryos via allontoic cavity route which showed sensitivity for virus isolation resulting in stunting and rounding of ...
M. Y. AL-Attar, F. F. AL-Haseerchy
doaj   +1 more source

Characterization of VRC01, a potent and broadly neutralizing anti-HIV mAb, produced in transiently and stably transformed tobacco [PDF]

open access: yes, 2014
The proposed clinical trial in Africa of VRC01, a potent broadly neutralizing antibody (bNAb) capable of neutralizing 91% of known HIV-1 isolates, raises concerns about testing a treatment which will be too expensive to be accessible by the most ...
EMEA   +4 more
core   +1 more source

Enhanced cell density cultivation and rapid expression-screening of recombinant Pichia pastoris clones in microscale

open access: yesScientific Reports, 2020
Cultivation of yeast Pichia pastoris in the microtiter plate, for optimisation of culture conditions, and expression screening of transformants has gained significance in recent years.
Neha Kaushik   +3 more
semanticscholar   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

open access: yesAdvanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu   +15 more
wiley   +1 more source

Canine adenovirus serotype 2 isolation and determination of its cultivation parameters

open access: yesВетеринария сегодня
Adenovirus infection in dogs caused by canine adenovirus serotype 2 predominantly results in respiratory disease typically manifested by respiratory tract lesions. Infectious laryngotracheitis is the most often recorded in dogs in the central part of the
A. A. Klimova
doaj   +1 more source

THE CULTIVATION OF THE GRANULES OF VACCINIA VIRUS [PDF]

open access: yesJournal of Experimental Medicine, 1926
The technique is described whereby vaccinia "granules" are separated from all other material of glycerolated vaccinia calf lymph and cultivated in vitro with embryonic tissues. These "granules"remain alive, as tested by rabbit corneal inoculation, for as long as 71 days, when grown in connection with growing tissue; they fail to remain ...
E C, Craciun, E H, Oppenheimer
openaire   +2 more sources

Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection [PDF]

open access: yes, 1984
Interstitial pneumonia linked with reactivation of latent human cytomegalovirus due to iatrogenic immunosuppression can be a serious complication of bone marrow transplantation therapy of aplastic anaemia and acute leukaemia1.
A Ebeling   +36 more
core   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy