Results 131 to 140 of about 143,533,111 (301)

Pneumonia, influenza virus A (H1N1) and atypical evolution in the Intensive Care Unit

Acta Médica del Centro, 2014
It is presented a patient of 50 years old, atypical in its evolution and its complications, he was hospitalized in February 2014 in the Intensive Care Unit of the  "Arnaldo Milian Castro"Surgical Hospital, City of Santa Clara, Villa Clara Province.
Francisco Cordié Muñoz, Wilder Reinoso Fernández, Sailys Rodríguez López   +2 more
doaj  

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

Advanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su, YiShan Xiong, Yuxuan Liang, Xiang Min, Daofeng Dai   +4 more
wiley   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

Advanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu   +8 more
wiley   +1 more source

Comparación entre las infecciones por influenza A (H1N1) y por influenza estacional en pacientes hospitalizados durante epidemia en el 2009

Revistas Argentina de Medicina, 2015
Introducción En abril de 2009 se informó de un brote de influenza A (H1N1), y en mayo en Argentina. Comparamos pacientes con influenza A (H1N1) e influenza estacional (IE).
Micaela Schiaffino, Bruno L Ferreyro, Vanina E Wainsztein, Nora Fuentes, Cristina Elizondo, Diego H Giunta, Luis Cámera, Florencia Cahn, Astrid Smud, Javier Altclas, Claudia Salgueira, Pablo Desmery, José Malvido, Beatriz Livellara, Gabriel Waisman, Laura Barcán   +15 more
doaj   +2 more sources

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

ANÁLISIS DEL MODELO NORMATIVO DE PREVENCIÓN SANITARIA DE INFLUENZA AVIAR EN COLOMBIA

Revista de la Facultad de Ciencias Agropecuarias, 2019
La influenza aviar es la enfermedad causada por la infección del virus de la familia Orthomixoviridae, género Influenza virus A, encontrándose de forma natural entre las aves acuáticas de todo el mundo y puede infectar a las aves de corral domésticas y a
Beatriz Elena Patiño Quiroz, Nicolas Ernesto Baldrich Romero, Sebastian Duque Patiño   +2 more
doaj  

Virus de la influenza: prevalencia, respuesta inmunitaria y pruebas de diagnóstico en la población infantil

MQRInvestigar
La enfermedad por influenza es una infección respiratoria viral aguda que históricamente hasta la actualidad ha causado un sinnúmero de morbimortalidad significativas en todo el mundo. El objetivo principal de esta revisión fue Analizar la Prevalencia, respuesta inmunitaria y pruebas de diagnóstico del virus de la influenza en la Población Infantil. La
Cindy Elizabeth Muentes-Bailon, Carmen Alexandra Suarez Quimis, Javier Martin Reyes-Baque   +2 more
openaire   +1 more source

Development of an influenza virus vaccine using the baculovirus-insect cell expression system : implications for pandemic preparedness [PDF]

, 2009
Key word Influenza, rHA, vaccine, baculovirus, insect cells, production, pandemic preparedness Influenza (or flu) is a highly contagious, acute viral respiratory disease that occurs seasonally in most parts of the world and is caused by influenza ...
Cox, M.M.J.
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