Results 241 to 250 of about 28,539 (272)

Development of CPA‐Catalyzed β‐Selective Reductive Amination of Cardenolides for the Synthesis and Biological Evaluation of Hydrolytically Stable Analogs

Chemistry – A European Journal, EarlyView.
We describe a new method to produce hydrolytically stable cardiotonic steroids using a CPA‐controlled diastereoselective reductive amination of cardenolide aglycones. The oleandrin and digitoxigenin analogs exhibited promising activity against various cancer cell lines in the NCI‐60 screen.
Natasha Perry, Shehab Eid, Gerold Schmitt‐Ulms, Pavel Nagorny   +3 more
wiley   +1 more source

Influenza vaccine outcomes: a meta-analysis revealing morbidity benefits amid low infection prevention. [PDF]

Eur Respir Rev
Presa J, Arranz-Herrero J, Alvarez-Losa L, Rius-Rocabert S, Pozuelo MJ, Lalueza A, Ochando J, Eiros JM, Sanz-Muñoz I, Nistal-Villan E.   +9 more
europepmc   +1 more source

A truncation mutant of adenomatous polyposis coli impairs apical cell extrusion through elevated epithelial tissue tension

Cytoskeleton, EarlyView.
Abstract Tissue tension encompasses the mechanical forces exerted on solid tissues within animal bodies, originating from various sources such as cellular contractility, interactions with neighboring cells and the extracellular matrix. Emerging evidence indicates that an imbalance in such forces can influence structural organization, homeostasis, and ...
Wan J. Gan, Rabina Giri, Jakob Begun, Helen E. Abud, Edna C. Hardeman, Peter W. Gunning, Alpha S. Yap, Ivar Noordstra   +7 more
wiley   +1 more source

Anti-RNApol3-Associated myocarditis: an emerging disease linking autoimmunity and infection. [PDF]

Ann Intensive Care
Quentric P, Charuel JL, Moyon Q, Hékimian G, Dorgham K, Lifermann F, Kerneis M, Mathian A, Aacha K, Melki I, Chommeloux J, Petit M, Gautier M, Bay P, Rouvier P, Charpentier E, da Mata-Jardin O, Lefevre L, Parizot C, Saura O, Levy D, Ortuno S, Schmidt M, Luyt CE, Gorochov G, Amoura Z, Combes A, Pineton de Chambrun M.   +27 more
europepmc   +1 more source

The global burden of swine influenza and its mitigation. [PDF]

Open Vet J
Meles DK, Khairullah AR, Rimayanti R, Mustofa I, Wurlina W, Utama S, Lestari TD, Mulyati S, Ahmad RZ, Moses IB, Wibowo S, Kusala MKJ, Wardhani BWK, Fauziah I, Kurniasih DAA, Anggraini L, Ekawasti F, Akintunde AO.   +17 more
europepmc   +1 more source

Deep Sequencing Reveals Dual Evolution of SARS-CoV-2: Insights Into Defective Genomes From Wuhan-Hu-1 Variants to Omicron Subvariants. [PDF]

J Med Virol
Campos C, Ibañez-Lligoña M, Colomer-Castell S, Gregori J, Garcia-Cehic D, Andrés C, Piñana M, González-Sánchez A, Rando-Segura A, Esperalba J, Saubí N, Cortese MF, Tabernero D, Rodriguez-Frias F, Ferrer R, Esteban JI, Kakze-van der Honing RW, Kampfraath AA, Vergara-Alert J, Segalés J, van der Poel WHM, Pumarola T, Antón A, Quer J.   +23 more
europepmc   +1 more source

Respiratory Syncytial Virus and Other Respiratory Viruses in Hospitalized Infants During the 2023-2024 Winter Season in Mexico. [PDF]

Viruses
Leija-Martínez JJ, Cadena-Mota S, González-Ortiz AM, Muñoz-Escalante JC, Mata-Moreno G, Hernández-Sánchez PG, Vega-Morúa M, Noyola DE.   +7 more
europepmc   +1 more source

Competition between transmission lineages mediated by human mobility shapes seasonal influenza epidemics in the US. [PDF]

Nat Commun
de Jong SPJ, Conlan AJK, Han AX, Russell CA.   +3 more
europepmc   +1 more source