Results 241 to 250 of about 143,533,111 (301)

Implementation of a SARS-CoV-2 genomic surveillance network as a strategy to face other health challenges in Peru. [PDF]

Rev Peru Med Exp Salud Publica
Padilla-Rojas C, Hurtado V, Lizarraga W, Jimenez-Vasquez V, Molina IS, Barcena-Flores L, Nuñez A, Sevilla N, Acedo-Lazo SV, Huamán-Angeles E, Medrano P, Izarra K, Fajardo A, Dominguez V, Vasquez K, Mestanza O, Ascue F, Bailon H, Galarza-Pérez M, Caceres-Rey O, Araujo-Castillo RV, Vargas-Herrera N, Huayra J, Arotinco-Garayar G, Lope-Pari P, Balbuena-Torres J, Rojas-Serrano N.   +26 more
europepmc   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

SPCE-Based Electrochemical Immunosensor for Influenza A (H1) Detection in Serum and Nasopharyngeal Samples. [PDF]

Biosensors (Basel)
Garza-Villegas MD, Luna-Cruz IE, Cavazos-Jaramillo AA, Mora-Hernández JM, Tamez-Guerra R, Rodríguez-Padilla C, Alcocer-González JM.   +6 more
europepmc   +1 more source

A Novel Sparse Cellular Labeling System with Tunable Gradients and Long‐Term Stability

Advanced Science, EarlyView.
The Tri‐M (Multi‐recombinase, Multi‐recognition site, and Multi‐nested) sparse cellular labeling system, built upon competitive recombination, integrates transgenic mice with viral injection to achieve tunable and long‐term stable sparse labeling of specific cell types with region selectivity, from sparse populations to individual cells, facilitating ...
Xiaomei Tang, Zhenye Hou, Li Lu, Yige Song, Changdong Chai, Lanfang Li, Yuhang Shen, Shuo Wang, Ya Zhao, Jinyu Zeng, Yiqing Guo, Fuliang Jiang, Zhigao Xiang, Hao Li, Aodi He, Bing Zhang, Youming Lu, Xinyan Li   +17 more
wiley   +1 more source

Post-Pandemic Resurgence and Seasonal Patterns of Influenza Viruses and Respiratory Syncytial Virus in Arequipa, Peru (2021-2023). [PDF]

Epidemiologia (Basel)
Chipana-Ramos C, Talavera YM, Zamudio-Rodriguez L, Villanueva-Sardon L, Carrasco AGM, Chacón RD, Ita-Balta Y.   +6 more
europepmc   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Strengthening One Health: Global Applications of the Joint Risk Assessment Operational Tool. [PDF]

Pathogens
Prasarnphanich OO, Dorjee S, Ahmad R, Brown R, Calvin S, Do H, Hoejskov PS, Ismayilova G, Kato M, Kuriata O, Lopes JK, Mahrous H, Scheuermann L, Traore T, Vrbova L, Waddell JT, Wannous C, Wulandari EW, Gongal G, de la Rocque S.   +19 more
europepmc   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Wastewater-Based Surveillance of Respiratory Viruses in the SARS-CoV-2 Post-Pandemic Period in Mexico. [PDF]

Viruses
Ulloa-Medina OU, Hernández-Sánchez PG, Mata-Moreno G, Jaime-Rocha LR, Alatorre-Camacho SDC, Lara-Hernández I, Comas-García M, Muñoz-Escalante JC, González-Ortiz AM, Torres-González P, Noyola DE.   +10 more
europepmc   +1 more source

Targeting the CRYAB/β‐Catenin Axis with an MMP‐9‐Responsive Hydrogel Disrupts CTC Clusters to Suppress Progression of Hepatocellular Carcinoma after Radiofrequency Ablation

Advanced Science, EarlyView.
The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen, Danni Yang, Songying Pi, Yuhan Liu, Hongbin Huang, Feile Ye, Yuhong Lin, Zhongzhen Su, Yongquan Huang   +8 more
wiley   +1 more source