Results 31 to 40 of about 28,539 (272)
Factores de riesgo para infección respiratoria aguda baja grave en Bogotá, 2001.
Biomédica: revista del Instituto Nacional de Salud, 2003 La gravedad de la infección respiratoria aguda (IRA) es mayor en países en desarrollo, sobre todo entre grupos social y económicamente pobres. Las neumonías virales son las más comunes, especialmente en niños.
María Belén Jaimes +8 more
doaj +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Preparación para un incremento de la circulación de los virus de influenza
Infectio, 2010 Hace un poco mas de 13 meses, se informo enel mundo la circulacion de un nuevo agentemicrobiano asociado a casos de infeccion respiratoriaaguda, el cual fue denominado porla Organizacion Mundial de la Salud (OMS)como el virus pandemico A H1N1 2009,tambien descrito por algunos investigadorescomo A H1N1v o A H1N1 pdm.Exactamente el 24 de abril de 2009 ...
openaire +3 more sources
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Medisur, 2011 Se realizan breves comentarios al artículo publicado en MediSur titulado “Formas clínicas graves de la influenza A H1N1. Lo que hemos aprendido de la atención a estos enfermos en Cienfuegos. MEDISUR 2009;7(5):3-7”. En los cuales se añade que existió una
Alfredo Darío Espinosa Brito
doaj +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
ASPECTOS BÁSICOS, CLÍNICOS Y EPIDEMIOLÓGICOS DE LA INFLUENZA
Revista de la Facultad de Medicina, 2009 En respuesta a la continua expansión del nuevo virus de influenza A H1N1, la Organización Mundial de la Salud (OMS) elevó mundialmente el nivel de alerta pandémica a Fase 6 el 11 de junio de 2009 y declaró que el mundo se encontraba en el comienzo de la ...
Orlando Acosta Losada +2 more
doaj
Structure of general-population antibody titer distributions to influenza A virus [PDF]
Scientific Reports, 2016 AbstractSeroepidemiological studies aim to understand population-level exposure and immunity to infectious diseases. Their results are normally presented as binary outcomes describing the presence or absence of pathogen-specific antibody, despite the fact that many assays measure continuous quantities.
Maciej F. Boni +25 more
openaire +9 more sources