HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Introducción: El virus de la gripe ocasiona anualmente epidemias estacionales con amplia extensión mundial y se estima que entre el 5 y el 20% de la población padece gripe cada año.
Marina Ignacio Torres +3 more
doaj +1 more source
Acerca de la influenza porcina (2009) [PDF]
Document is in Spanish and English.La influenza porcina (gripe porcina) es un tipo de influenza que afecta por lo general a los cerdos. En la actualidad, este virus se está transmitiendo de persona a persona. Se han reportado casos en personas en los EE.
core
An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism. [PDF]
Influenza viruses cause seasonal flu each year and pandemics or epidemic sporadically, posing a major threat to public health. Recently, a new influenza D virus (IDV) was isolated from pigs and cattle. Here, we reveal that the IDV utilizes 9-O-acetylated
Chen, Xi +8 more
core +3 more sources
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
La influenza, un problema vigente de salud pública Influenza, an existing public health problem
La influenza estacional es una enfermedad respiratoria aguda, recurrente y común que se conoce desde la antigüedad y se presenta sobre todo durante los meses de invierno con un elevado impacto para la salud pública mundial.
Juan García-García, Celso Ramos
doaj
Evaluación de anticuerpos anti-m1 sobre la neutralización del virus influenza A [PDF]
La influenza es una enfermedad reemergente altamente contagiosa responsable de panzootias, epizootias y pandemias en la población humana y animal. El agente causal de esta enfermedad es el virus Influenza A.
Plata Hipólito, Claudia Bernardette
core
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
La miocarditis es una enfermedad inflamatoria del miocardio. Las infecciones virales son la causa más común, aunque también puede deberse a reacciones de hipersensibilidad y de etiología autoinmunitaria, entre otras.
Edwin Silva +6 more
doaj +1 more source
The production and development of H7 Influenza virus pseudotypes for the study of humoral responses against avian viruses [PDF]
In recent years, high pathogenicity avian influenza (HPAI) virus, H5N1, low pathogenicity avian influenza (LPAI) virus, H9N2, and both HPAI and LPAI H7 viruses have proved devastating for the affected economies reliant on poultry industry, and have posed
Böttcher-Frieberthäuser, Eva +5 more
core +3 more sources

