Results 71 to 80 of about 143,533,111 (301)

Intra- and interspecies transmission of H7N7 highly pathogenic avian influenza virus during the avian influenza epidemic in the Netherlands in 2003 [PDF]

, 2009
The poultry epidemic of H7N7 highly pathogenic avian influenza (HPAI) virus in the Netherlands in 2003 was probably the result of the introduction of an H7N7 low pathogenic avian influenza (LPAI) virus (by interspecies transmission from wild birds) and ...
Goot, J.A., van der, Stegeman, J.A., Jong, M.C.M., de, Koch, G.   +3 more
core  

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Studies on influenza A virus PB1-F2 protein [PDF]

, 2011
The influenza A virus genome codes for up to 12 proteins. Segment 2 encodes three proteins, the polymerase subunit PB1, a small protein PB1-F2 and an N-terminally truncated version of PB1 called N40. Different functions have been reported for PB1-F2 such
Vater, Sandra
core   +2 more sources

Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression. [PDF]

, 2011
Glycyrrhizin is known to exert antiviral and anti-inflammatory effects. Here, the effects of an approved parenteral glycyrrhizin preparation (Stronger Neo-Minophafen C) were investigated on highly pathogenic influenza A H5N1 virus replication, H5N1 ...
Michaelis, Martin, Sithisarn, Patchima, Leutz, Anke, Cinatl, Jindrich, Martin Michaelis, Geiler Janina, Patrizia Naczk, Geiler, Janina, Doerr, Hans Wilhelm, Naczk, Patrizia, Sithisarn Patchima, Anke Leutz, Janina Geiler, Patchima Sithisarn, Hans Wilhelm Doerr, Jindrich Cinatl, Doerr Hans Wilhelm, Naczk Patrizia, Cinatl Jindrich, Leutz Anke, Michaelis Martin   +20 more
core   +2 more sources

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Reporte de casos por infección de virus de Influenza A H1N1: Hallazgos de autopsia

Revista de Ciencias Forenses de Honduras, 2018
La influenza continúa siendo una causa importante de muerte en las Américas; en nuestro país al igual que en otros países del continente, hay circulación viral sostenida del virus Influenza H1N1pdm09, este reporte describe los hallazgos histopatológicos
Enoe Arely Vásquez, Mireya Matamoros, Nicolás Sabillón   +2 more
doaj   +1 more source

Functional domains of the influenza A virus PB2 protein:identification of NP- and PB1-binding sites [PDF]

, 2004
Influenza virus genomic RNA segments are packaged into ribonucleoprotein (RNP) structures by the PB1, PB2, and PA subunits of an RNA polymerase and a single-strand RNA-binding nucleoprotein (NP).
Poole, Emma, Digard, Paul, Medcalf, Liz, Elton, Debra, Poole, Emma L   +4 more
core   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Factores de riesgo asociados a mortalidad por nueva influenza A (H1N1) en la región Cusco-Perú

Acta Médica Peruana, 2013
Introducción: En la Región Cusco durante el 2009, se reportaron 395 casos confirmados de nueva influenza A(H1N1) y 15 defunciones. La tasa de letalidad del 3.8%, estuvo muy por encima de reportes nacionales e internacionales, constituyéndose en serio ...
Pablo F. Grajeda Annca, Oscar Filipo Niño de Guzmán, Manuel Montoya Lizarraga, Yuri Guevara Fernández   +3 more
doaj  

Insights into neutralization of animal viruses gained from study of influenza virus [PDF]

, 1991
It has long been known that the binding of antibodies to viruses can result in a loss of infectivity, or neutralization, but little is understood of the mechanism or mechanisms of this process.
Outlaw, Mark C., Dimmock, N. J.
core   +1 more source