Results 81 to 90 of about 143,533,111 (301)
Advanced Materials Technologies, EarlyView.Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina +5 more
wiley +1 more source
Pandemia de influenza A por nuevo virus H1N1
Revista de la Facultad de Medicina, 2009 Durante varias décadas hemos esperado la reaparición de un virus nuevo de influenza. Durante los últimos 10 años, inicialmente el SARS (1) y posteriormente, la influenza aviar H5N1 (2), aparecieron y fueron tomados inicialmente como la esperada epidemia ...
Jorge Alberto Cortés
doaj
Medisan, 2010 Se presenta el primer caso clínico de un adolescente de 11 años de edad, ingresado en la Unidad de Cuidados Progresivos del Hospital Infantil Norte "Dr. Juan de la Cruz Martínez Maceira" de Santiago de Cuba por presentar, desde hacía 4 días, malestar general, fiebre, tos, dolor en la garganta y falta de aire. Se diagnosticó una neumonía adquirida en la
Heriberto Arencibia Sosa +4 more
openaire +1 more source
Preparación para un incremento de la circulación de los virus de influenza
Infectio, 2010 Hace un poco mas de 13 meses, se informo enel mundo la circulacion de un nuevo agentemicrobiano asociado a casos de infeccion respiratoriaaguda, el cual fue denominado porla Organizacion Mundial de la Salud (OMS)como el virus pandemico A H1N1 2009,tambien descrito por algunos investigadorescomo A H1N1v o A H1N1 pdm.Exactamente el 24 de abril de 2009 ...
openaire +2 more sources
Mecanismos de inflamación y coagulación en la patogenia del virus de influenza A
, 2021 Influenza A virus H1N1 (2009) is considered a global health emergency; it has been described that during 2009 caused between 151,700 and 575,400 deaths worldwide, affecting mostly people under 65 years. Influenza viruses commonly infect the upper respiratory tract resulting in a limited infection, but in severe cases the viruses can reach the lower ...
openaire +2 more sources
Advanced Science, EarlyView.IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu +8 more
wiley +1 more source
The multifunctional NS1 protein of influenza A viruses [PDF]
, 2008 The non-structural (NS1) protein of influenza A viruses is a non-essential virulence factor that has multiple accessory functions during viral infection.
Hale, Benjamin Geoffrey +7 more
core +2 more sources
Revista Peruana de Medicina Experimental y Salud Pública, 2011 Objetivos. Determinar las características clínicas y demográficas de la neumonía por el virus de influenza AH1N1/2009 pandémico en un hospital de referencia de Perú. Materiales y métodos.
Edwin Miranda-Choque +7 more
doaj
Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences
Advanced Science, EarlyView.This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu +7 more
wiley +1 more source