Results 41 to 50 of about 124,032 (305)

Estudi genètic dels virus de la influença A circulants en porcs a Espanya [PDF]

, 2014
Un estudi genètic dels virus de la influença A circulants en porcs al nord-est d'Espanya durant el període 2006-2007 revela la seva pertinença a tres subtipus de soques de grip porcina.
Montoya González, María
core   +1 more source

An unbiased genetic screen reveals the polygenic nature of the influenza virus anti-interferon response. [PDF]

, 2014
Influenza A viruses counteract the cellular innate immune response at several steps, including blocking RIG I-dependent activation of interferon (IFN) transcription, interferon (IFN)-dependent upregulation of IFN-stimulated genes (ISGs), and the activity
Asensio, VJ, Bengoechea, JA, Fernández, Y, Killip, MJ, Oliveros, JC, Ortín, J, Pérez-Cidoncha, M, Randall, RE   +7 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Factores de riesgo para infección respiratoria aguda baja grave en Bogotá, 2001.

Biomédica: revista del Instituto Nacional de Salud, 2003
La gravedad de la infección respiratoria aguda (IRA) es mayor en países en desarrollo, sobre todo entre grupos social y económicamente pobres. Las neumonías virales son las más comunes, especialmente en niños.
María Belén Jaimes, Diana C. Cáceres, Fernando de la Hoz, Camilo Gutiérrez, Diana Herrera, Jairo Pinilla, Alexandra Porras, Fabio Rodríguez, Martha Velandia   +8 more
doaj   +1 more source

Histoire naturelle d'un virus zoonotique en mode insulaire : cas de la propagation du virus grippal pandémique H1N1p 2009 à la Réunion, de l'homme au porc, il n'y a qu'un pas [PDF]

, 2011
Bien que n'ayant jamais été identifié chez le porc avant d'être détecté chez l'Homme, il a été craint, dès l'émergence du virus influenza A/H1N1 responsable de la pandémie de 2009 (pH1N1), que ce multi-réassortant n'ait la capacité de transgresser ...
Bonnet-Madin, L., Cardinale, Eric, De Lamballerie, Xavier, Dellagi, Koussay, Hervé, Sèverine, Hoarau, Johny, Pascalis, Hervé, Porphyre, Vincent, Roger, Matthieu, Simon, Gaëlle, Temmam, Sarah, Turpin, Magali   +11 more
core  

Trends of influenza B during the 2010–2016 seasons in 2 regions of north and south Italy: The impact of the vaccine mismatch on influenza immunisation strategy [PDF]

, 2018
Influenza A and B viruses are responsible for respiratory infections, representing globally seasonal threats to human health. The 2 viral types often co-circulate and influenza B plays an important role in the spread of infection.
Alicino C., Ansaldi F., Calamusa G., Canepa P., Colomba G. M. E., Orsi A., Pojero F., Tramuto F., Trucchi C., Vitale F.   +9 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Aspectos básicos, clínicos y epidemiológicos de la Influenza

Revista de la Facultad de Medicina, 2009
En respuesta a la continua expansión del nuevo virus de influenza A H1N1, la Organización Mundial de la Salud (OMS) elevó mundialmente el nivel de alerta pandémica a Fase 6 el 11 de junio de 2009 y declaró que el mundo se encontraba en el comienzo de la ...
Orlando Acosta Losada, Carlos Arturo Guerrero Fonseca, Jorge A. Cortés   +2 more
doaj  

Nuevos virus respiratorios en niños de 2 meses a 3 años con sibilancias recurrentes [PDF]

, 2008
Introducción. Los virus respiratorios son los agentes que con más frecuencia desencadenan sibilancias, especialmente, el virus sincicial respiratorio en los lactantes y los rinovirus en niños mayores. Objetivos.
Barrero, Paola, Fuse, Valentina, Maffey, Alberto, Mistchenko, Alicia Susana, Márques, María de los Ángeles, Saia, Mariana, Teper, Alejandro, Venialgo, Carolina, Villalba, Analía   +8 more
core  

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source