Results 71 to 80 of about 1,115,168 (306)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Diseases [PDF]

, 1988
To download the whole book, click here.A review is made of diseases of cultured Penaeus monodon , examining the diagnosis and pathology of the disease or disease agents involved and their prevention and control.
Baticados, Ma. Cecilia L.
core   +1 more source

Reconstitution of interferon regulatory factor 7 expression restores interferon beta induction in Huh7 cells

Journal of Virology
Abundance of essential components of double-stranded RNA (dsRNA) recognition and the subsequent interferon (IFN) response vary widely between primary human hepatocytes (PHHs) and commonly used cell culture models based on derivatives of Huh7 cells ...
Andreas Betz, Hao-En Huang, Zuguang Gu, Ombretta Colasanti, Teng-Feng Li, Jasper Hesebeck-Brinckmann, Nadine Gillich, Gnimah Eva Gnouamozi, Matthias Schlesner, Florian W. R. Vondran, Stephan Urban, Ralf Bartenschlager, Marco Binder, Volker Lohmann   +13 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Endogenous Viral Etiology of Prion Diseases [PDF]

, 2009
Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a group of incurable neurodegenerative disorders, including Kuru and Creutzfeldt-Jakob disease in humans, “mad cow” disease in cattle, and scrapie in sheep. This paper
Claudiu I. Bandea
core   +1 more source

In silico screening and experimental validation identify riboflavin as an RNA-targeted antiviral against SARS-CoV-2

Scientific Reports
This study explored drug repurposing strategies against conserved RNA structures in the SARS-CoV-2 genome to address viral mutation challenges. Conserved RNA elements were computationally identified by aligning 283 SARS-CoV-2 genomes from Korean patients.
Chae-Hong Jeong, Yoo Jin Na, Tae Yong Kim, So Young Lee, Jungyeon Kim, Sangmi Ryou   +5 more
doaj   +1 more source

The practitioners guide for dealing with the novel Influenza A, H1n1 pandemic

South African Family Practice, 2009
Within three months of its discovery, the new Influenza A (H1n1) swineflu strain has spread to such an extent that a pandemic has been declared by the World Health Organization (WHO). Although most cases seem to be mild, cases of severe disease have also
Marietjie Venter, L. Bloomberg
doaj   +1 more source

A comparative analysis depicting the disease characteristics and phylogenetic signature of human cytomegalovirus infection in Human Immunodeficiency Virus 1 seropositive patients with end-organ retinitis and gastro-enteric diseases

Scientific Reports, 2022
During advanced HIV infection, Human Cytomegalovirus (HCMV) has been proven to produce devitalizing end-organ diseases (EOD). The interactive co-existence of HIV and HCMV has been reported by many researchers and has been suggested to be linked with a ...
Aroni Chatterjee, Debsopan Roy, Sumit Mukherjee, Hiya Ghosh, Agnibha Maiti, Rivu Basu, Nilanjan Chakraborty   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host [PDF]

, 2013
Schmallenberg virus (SBV) is an emerging orthobunyavirus of ruminants associated with outbreaks of congenital malformations in aborted and stillborn animals.
Gerald Barry, Beer Martin, Kohl, Alain, Kerstin Hahn, Schnettler Esther, Alain Kohl, Glass, M., Barry Gerald, Lamm Catherine, Martin Beer, Vanessa Herder, Mcgregor, Eva, Piras, Ilaria M., Murgia, Claudio, Herder, V., Schnettler, E., Anna Janowicz, Lamm, C., Caporale Marco, Baumgärtner, Wolfgang., Shaw, Andrew, Murgia Claudio, McGregor Eva, Palmarini, Massimo, Melanie McFarlane, Janowicz, Anna, Piras, I.M., McFarlane, Melanie, Kohl Alain, Barry, Gerald, Janowicz, A., Schnettler, Esther, Claudio Murgia, McGregor, E., Piras Ilaria M., Lamm, Catherine, Beer, Martin, Eva McGregor, Hahn, K., Caporale, M., Baumgärtner, W., Catherine Lamm, Esther Schnettler, Kohl, A., Palmarini, M., Varela, M., Mandy Glass, Murgia, C., Baumgärtner Wolfgang, Mariana Varela, Janowicz Anna, Piras, Ilaria, Varela Mariana, Ilaria M Piras, Hahn, Kerstin, Shaw, A., Varela, Mariana, McFarlane Melanie, Herder Vanessa, McFarlane, M., Palmarini Massimo, Shaw Andrew, Herder, Vanessa, Wolfgang Baumgärtner, Glass, Mandy, Andrew Shaw, Baumgärtner, Wolfgang, Marco Caporale, Massimo Palmarini, Barry, G., Hahn Kerstin, Caporale, Marco, Glass Mandy   +72 more
core   +1 more source