Results 71 to 80 of about 4,275,355 (312)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Microbiology Spectrum, 2016 ABSTRACT The history of Zika virus disease serves as a paradigm of a typical emerging viral infection. Zika virus disease, a mosquito-borne flavivirus, was first isolated in 1947 in the Zika forest of Uganda. The same virus was also isolated from jungle-dwelling mosquitoes ( Aedes [ Stegomyia
openaire +2 more sources
Culicoides and midge-associated arboviruses on cattle farms in Yunnan Province, China
ParasiteCulicoides spp. (Diptera: Ceratopogonidae) are small biting midges, some of which are the vectors of arboviruses affecting livestock, i.e., African horse sickness virus (AHSV), bluetongue virus (BTV), and epizootic hemorrhagic disease virus (EHDV ...
Duan Ying-Liang +8 more
doaj +1 more source
The detection of 3 ambiguous type 2 vaccine-derived polioviruses (VDPV2s) in Uganda
Virology Journal, 2018 Background The Oral Polio Vaccine (OPV or Sabin) is genetically unstable and may mutate to form vaccine-derived polioviruses (VDPVs). Methods In 2014, two VDPVs type 2 were identified during routine surveillance of acute flaccid paralysis (AFP) cases ...
Mary Bridget Nanteza +9 more
doaj +1 more source
BMC Primary Care, 2023 Background The rate of progression of type 2 diabetes following diagnosis varies across individuals and populations. Studies investigating the progression of type 2 diabetes in adult African populations with newly diagnosed diabetes are limited. We aimed
Davis Kibirige +3 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
A review of the diseases of cultured penaeid shrimps and prawns with emphasis on recent discoveries and developments [PDF]
, 1985 The development of the commercial culture of penaeid shrimps and prawns has been accompanied by the occurrence of diseases of infectious and noninfectious etiologies.
Lightner, Donald V.
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source