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Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang +10 more
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Plant virus: Diversity and ecology
, 2021Plant viruses are parasites that infect plants and create great economic loss worldwide, especially agriculture-based countries. The management of virus diseases is still challenging due to the high mutation rate of viral genomes.
S. Riyaz, D. Jesse, K. Kathiravan
semanticscholar +2 more sources
Plant Virus Diversity and Evolution
Historically, the majority of plant virology focused on agricultural systems. Recent efforts have expanded our knowledge of the true diversity of plant viruses by studying those viruses that infect wild, undomesticated plants. Those efforts have provided
A. H. Stobbe, M. Roossinck
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RNA virus diversity in rodents
Archives of Microbiology, 2023Many zoonotic disease emergencies are associated with RNA viruses in rodents that substantially impact public health. With the widespread application of meta-genomics and meta-transcriptomics for virus discovery over the last decade, viral sequences deposited in public databases have expanded rapidly, and the number of novel viruses discovered in ...
Yayu Fan +5 more
semanticscholar +3 more sources
Virus diversity and evolution.
Current Opinion in Microbiology, 2013C. Arias
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Virus load and antigenic diversity
Bulletin of Mathematical Biology, 1997In this paper, we analyse mathematical models for the interaction between virus replication and immune responses. We show that the immune system can provide selection pressure for or against viral diversity. The paper provides new insights into the relationship between virus load (=the abundance of virus in an infected individual) and antigenic ...
B, Bittner, S, Bonhoeffer, M A, Nowak
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Hepatitis B virus genetic diversity
Journal of Medical Virology, 2006Hepatitis B virus (HBV) is a human DNA virus, which replicates through an RNA intermediate because of the reverse-transcriptase (RT) activity of its DNA polymerase. As a result, the mutation rate for HBV is higher than the rate observed for most DNA viruses. HBVs are classified into genotypes based on genomic sequencing, and antigenic subtypes based on
José M, Echevarría, Ana, Avellón
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Diversity of African swine fever virus
American Journal of Veterinary Research, 1985SUMMARY An African swine fever virus is an heterogeneous population, consisting of clones having different biological characteristics in respect to hemadsorption, virulence, infectivity, plaque size, and antigenic determinants. The following observations were made: (1) Nonhemadsorbing virus (nhv) have been segregated from field isolates from Haiti (ht ...
I C, Pan, W R, Hess
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Genetic diversity of Wheat dwarf virus
Archives of Virology, 2002The complete sequence of a new wheat-infecting isolate of Wheat dwarf virus from Sweden (WDV-[Enk1]) was determined, as well as a 726-nt region covering part of rep and the long intergenic region (LIR) of six other wheat-infecting Swedish isolates and a barley-infecting isolate from Hungary (WDV-Bar[HU]).
A, Kvarnheden +3 more
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Genetic Diversity of Simian Immunodeficiency Virus
Journal of Medical Primatology, 1989We have demonstrated that the genetic diversity of simian immunodeficiency virus from African green monkeys (SIVagm) is much greater than that observed previously for individual HIV‐1, HIV‐2, or SIVmac isolates. Extensive genetic variation among SIVagm isolates and the high prevalence of green monkey infection without disease suggest that the virus has
Y, Li +4 more
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