Results 141 to 150 of about 2,750,709 (301)
Frontiers in MicrobiologyBovine respiratory syncytial virus (BRSV) is an RNA virus with envelope that causes acute, febrile, and highly infectious respiratory diseases in cattle. However, the manner and mechanism of BRSV entry into cells remain unclear.
Yang Liu +6 more
doaj +1 more source
Virus-host interactions : entry and replication of Crimean-Congo hemorrhagic fever virus
, 2014 Crimean-Congo hemorrhagic fever (CCHF) is a severe acute human disease with potential lethal outcome caused by a virus, Crimean-Congo hemorrhagic fever virus (CCHFV).
Cecilia Johansson (18681835)
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Herpes simplex virus entry and the significance of glycoproteingH.
, 2006 Herpes simplex virus entry and the significance of ...
Perry Michael. Scanlan (7966904)
core +3 more sources
Insilico targeting of virus entry facilitator NRP1 to block SARS-CoV2 entry.
PLoS ONEThe entry and infectivity of a virus are determined by its interaction with the host. SARS-CoV-2, the virus responsible for COVID-19, utilizes the spike (S) protein to attach to and enter host cells.
Nousheen Bibi +4 more
doaj +2 more sources
Correction: Small-Molecule Inhibitors of Dengue-Virus Entry
, 2019 Correction: Small-Molecule Inhibitors of Dengue-Virus ...
Priscilla L. Yang (173985) +3 more
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
IFITM3 at the viral fusion-pore checkpoint: membrane energetics and entry-route-dependent outcomes
Frontiers in ImmunologyInterferon-induced transmembrane proteins (IFITMs) are small interferon-stimulated membrane proteins that can limit viral entry, but their effects depend on the virus, entry route, and experimental context. This Mini Review focuses on IFITM3 at the viral
Luyu Mao +8 more
doaj +1 more source