Results 101 to 110 of about 4,863,377 (394)

Zoonotic Origins of Human Metapneumovirus: A Journey from Birds to Humans

Viruses, 2022
Metapneumoviruses, members of the family Pneumoviridae, have been identified in birds (avian metapneumoviruses; AMPV’s) and humans (human metapneumoviruses; HMPV’s).
Sonja T. Jesse, Martin Ludlow, Albert D. M. E. Osterhaus   +2 more
doaj   +1 more source

Chikungunya virus evolution following a large 3′UTR deletion results in host-specific molecular changes in protein-coding regions

Virus Evolution, 2018
The 3′untranslated region (UTR) in alphavirus genomes functions in virus replication and plays a role in determining virus host range. However, the molecular evolution of virus UTRs is understudied compared to the evolution of protein-coding regions ...
Valerie J. Morley, Maria G. Noval, Rubing Chen, S. Weaver, M. Vignuzzi, Kenneth A. Stapleford, P. Turner   +6 more
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Evolutionary Insight into the Association between New Jersey Polyomavirus and Humans

Viruses, 2023
Advances in viral discovery techniques have led to the identification of numerous novel viruses in human samples. However, the low prevalence of certain viruses in humans raises doubts about their association with our species.
Aref-Abdolllah Aghebatrafat, Chris Lauber, Kevin Merkel, Barbara Fruth, Kevin Langergraber, Martha M. Robbins, Roman M. Wittig, Fabian H. Leendertz, Sébastien Calvignac-Spencer   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression

Viruses, 2017
The apolipoprotein B messenger RNA-editing, enzyme-catalytic, polypeptide-like 3 (APOBEC3) family of cytidine deaminases plays an important role in the innate immune response to viral infections by editing viral genomes.
Cody J. Warren, Joseph A. Westrich, Koenraad Van Doorslaer, Dohun Pyeon   +3 more
doaj   +1 more source

Establishing an In Vitro System to Assess How Specific Antibodies Drive the Evolution of Foot-and-Mouth Disease Virus

Viruses, 2022
Viruses can evolve to respond to immune pressures conferred by specific antibodies generated after vaccination and/or infection. In this study, an in vitro system was developed to investigate the impact of serum-neutralising antibodies upon the evolution
David J. King, Graham Freimanis, Chris Neil, Andrew Shaw, Tobias J. Tuthill, Emma Laing, Donald P. King, Lidia Lasecka-Dykes   +7 more
doaj   +1 more source

The production and development of H7 Influenza virus pseudotypes for the study of humoral responses against avian viruses [PDF]

, 2013
In recent years, high pathogenicity avian influenza (HPAI) virus, H5N1, low pathogenicity avian influenza (LPAI) virus, H9N2, and both HPAI and LPAI H7 viruses have proved devastating for the affected economies reliant on poultry industry, and have posed
Böttcher-Frieberthäuser, Eva, Cattoli, Giovanni, Ferrara, Francesca, Molesti, Eleonora, Temperton, Nigel, Terregino, Calogero   +5 more
core   +3 more sources

Avian Influenza Viruses in Wild Birds: Virus Evolution in a Multihost Ecosystem

Journal of Virology, 2018
Wild ducks and gulls are the major reservoirs for avian influenza A viruses (AIVs). The mechanisms that drive AIV evolution are complex at sites where various duck and gull species from multiple flyways breed, winter, or stage. The Republic of Georgia is
D. Venkatesh, M. Poen, T. Bestebroer, R. Scheuer, O. Vuong, M. Chkhaidze, A. Machablishvili, Jimsher Mamuchadze, L. Ninua, Nadia B. Fedorova, R. Halpin, Xudong Lin, Amy Ransier, Timothy B. Stockwell, D. Wentworth, Divya Kriti, Jayeeta Dutta, H. van Bakel, Anita Puranik, M. Slomka, S. Essen, I. Brown, R. Fouchier, N. Lewis   +23 more
semanticscholar   +1 more source

What Does Virus Evolution Tell Us About Virus Origins? [PDF]

Journal of Virology, 2011
ABSTRACTDespite recent advances in our understanding of diverse aspects of virus evolution, particularly on the epidemiological scale, revealing the ultimate origins of viruses has proven to be a more intractable problem. Herein, I review some current ideas on the evolutionary origins of viruses and assess how well these theories accord with what we ...
openaire   +3 more sources