Results 61 to 70 of about 4,863,377 (394)

Identification of drug resistance mutations in HIV from constraints on natural evolution [PDF]

, 2015
Human immunodeficiency virus (HIV) evolves with extraordinary rapidity. However, its evolution is constrained by interactions between mutations in its fitness landscape.
Barton, John P., Butler, Thomas C., Chakraborty, Arup K., Kardar, Mehran   +3 more
core   +2 more sources

Oropouche virus: clinical, epidemiological, and molecular aspects of a neglected orthobunyavirus. [PDF]

, 2017
Oropouche virus (OROV) is an important cause of arboviral illness in Latin American countries, more specifically in the Amazon region of Brazil, Venezuela and Peru, as well as in other countries such as Panama.
Acrani, Gustavo Olszanski, Cardoso, Jedson Ferreira, da Rosa, Jorge Fernando Travassos, de Paula Pinheiro, Francisco, de Souza, William Marciel, Figueiredo, Mário Luiz, Nunes, Márcio Roberto Teixeira   +6 more
core   +1 more source

Insect-specific virus evolution and potential effects on vector competence

Virus genes, 2019
The advancement in high-throughput sequencing technology and bioinformatics tools has spurred a new age of viral discovery. Arthropods is the largest group of animals and has shown to be a major reservoir of different viruses, including a group known as ...
Pontus Öhlund, H. Lundén, A. Blomström   +2 more
semanticscholar   +1 more source

Determinants of Virus Variation, Evolution, and Host Adaptation

Pathogens, 2022
Virus evolution is the change in the genetic structure of a viral population over time and results in the emergence of new viral variants, strains, and species with novel biological properties, including adaptation to new hosts.
Katherine LaTourrette, H. García-Ruíz
semanticscholar   +1 more source

Deep mutational scanning and CRISPR-engineered viruses: tools for evolutionary and functional genomics studies

mSphere
Recent advancements in synthetic biology and sequencing technologies have revolutionized the ability to manipulate viral genomes with unparalleled precision.
Mercedes Paz, Gonzalo Moratorio
doaj   +1 more source

The mode and tempo of hepatitis C virus evolution within and among hosts

BMC Evolutionary Biology, 2011
Background Hepatitis C virus (HCV) is a rapidly-evolving RNA virus that establishes chronic infections in humans. Despite the virus' public health importance and a wealth of sequence data, basic aspects of HCV molecular evolution remain poorly understood.
Salemi Marco, Lemey Philippe, Parker Joe, Gray Rebecca R, Katzourakis Aris, Pybus Oliver G   +5 more
doaj   +1 more source

Inferring stabilizing mutations from protein phylogenies : application to influenza hemagglutinin [PDF]

, 2009
One selection pressure shaping sequence evolution is the requirement that a protein fold with sufficient stability to perform its biological functions.
A Akasako, A Akasako, A Cao, A Martin, A Mitraki, A Rambaut, AA Pakula, AR Dinner, AR Fersht, AR Fersht, AS Yang, AS Yang, AV Gribenko, B Steipe, B Steipe, BM Broome, C Pal, C Park, CB Anfinsen, CB Do, CM Dobson, CT Saunders, D Gilis, D Perl, D Shortle, DA Cowan, DA Drummond, DA Drummond, DD Loeb, DM Taverna, DM Taverna, E Capriotti, E Hoffmann, E van Nimwegen, EPC Rocha, Eugene I. Shakhnovich, F Chiti, F Ronquist, G Parisi, GG Brownlee, H Akashi, H Li, H Schindelin, H Zhao, H Zhou, HW Hellinga, I Keller, IE Sanchez, IMP del Pino, J Felsenstein, J Felsenstein, J Felsenstein, J Felsenstein, J Kyte, JA Wells, JB Garrett, JD Bloom, JD Bloom, JD Bloom, JD Bloom, Jesse D. Bloom, JL Thorne, JM Koshi, JP Huelsenbeck, JP Huelsenbeck, JR Cochran, JR Lepock, JV Chamary, K Ishikawa, K Ishikawa, K Katayanagi, KA Bava, KA Gray, KB Zeldovich, KJ Szretter, KL Maxwell, L Giver, L Serrano, M Dai, M Haruki, M Jacob, M Lehmann, M Matrosovich, M Ueda, M Wunderlich, Matthew J. Glassman, MD Kumar, MF Sippl, MM Garcia-Mira, MM Gromiha, MP Canadillas, MS Fornasari, MW Pantoliano, N Amin, N Goldman, N Goldman, N Lartillot, N Tong, R Godoy-Ruiz, R Godoy-Ruiz, R Godoy-Ruiz, R Guerois, R Rabadan, R Sakaue, RC Edgar, RJ Ellis, S Govindarajan, S Kimura, S Kimura, S Nakajima, S Sato, SC Choi, SH White, SJ Gamblin, SS Jaswal, U Bastolla, V Parthiban, VG Dugan, VN Uversky, W Besenmatter, WS Sandberg, WSW Wong, XJ Zhang, Y Bao, YY Tseng, Z Chen   +125 more
core   +3 more sources

A multi-group SEIRA model for the spread of COVID-19 among heterogeneous populations [PDF]

, 2020
The outbreak and propagation of COVID-19 have posed a considerable challenge to modern society. In particular, the different restrictive actions taken by governments to prevent the spread of the virus have changed the way humans interact and conceive ...
Biron-Lattes, Juan Pablo, Contreras, Sebastian, Medina-Ortiz, David, Olivera-Nappa, Alvaro, Villavicencio, H. Andres   +4 more
core   +2 more sources

The Ecology and Evolution of Japanese Encephalitis Virus

Pathogens, 2021
Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus mainly spread by Culex mosquitoes that currently has a geographic distribution across most of Southeast Asia and the Western Pacific. Infection with JEV can cause Japanese encephalitis (JE),
P. Mulvey, V. Duong, S. Boyer, G. Burgess, David T. Williams, P. Dussart, P. Horwood   +6 more
semanticscholar   +1 more source

Molecular epidemiology and pathogenicity of H5N1 and H9N2 avian influenza viruses in clinically affected chickens on farms in Bangladesh

Emerging Microbes and Infections, 2021
Avian influenza virus (AIV) subtypes H5N1 and H9N2 co-circulate in poultry in Bangladesh, causing significant bird morbidity and mortality. Despite their importance to the poultry value chain, the role of farms in spreading and maintaining AIV infections
Ripatun Nahar Ripa, Joshua E. Sealy, Jayna Raghwani, Tridip Das, Himel Barua, Md. Masuduzzaman, A. K. M. Saifuddin, Md. Reajul Huq, Mohammad Inkeyas Uddin, Munir Iqbal, Ian Brown, Nicola S. Lewis, Dirk Pfeiffer, Guillaume Fournie, Paritosh Kumar Biswas   +14 more
doaj   +1 more source