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Virus-like Particles: Measures and Biological Functions
Viruses, 2022 Virus-like particles resemble infectious virus particles in size, shape, and molecular composition; however, they fail to productively infect host cells.
Tara Bhat, Amy Cao, John Yin
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Minimal system for assembly of SARS-CoV-2 virus like particles
Scientific Reports, 2020 SARS-CoV-2 virus is the causative agent of COVID-19. Here we demonstrate that non-infectious SARS-CoV-2 virus like particles (VLPs) can be assembled by co-expressing the viral proteins S, M and E in mammalian cells.
Heather Swann +7 more
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Platelet-like particles released from Ebola virus-infected megakaryocytic cells behave like virus-like particles. [PDF]
PLoS PathogensEbola virus (EBOV) is likely a zoonotic and re-emerging virus that causes severe outbreaks of Ebola virus disease. The virus spreads to various tissues during the late stage of infection and has been detected in immune-privileged sites of survivors ...
Makoto Kuroda, Peter J Halfmann
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Characterization of chikungunya virus-like particles. [PDF]
PLoS ONE, 2014 Chikungunya virus (CHIKV) is becoming a global concern due to the increasing number of outbreaks throughout the world and the absence of any CHIKV-specific vaccine or treatment.
Nitchakarn Noranate +5 more
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Recent Progress on the Versatility of Virus-Like Particles
Vaccines, 2020 Virus-like particles (VLPs) are multimeric nanostructures composed of one or more structural proteins of a virus in the absence of genetic material. Having similar morphology to natural viruses but lacking any pathogenicity or infectivity, VLPs have ...
Ciying Qian +10 more
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Virus like particles as a platform for cancer vaccine development [PDF]
PeerJ, 2017 Cancers have killed millions of people in human history and are still posing a serious health problem worldwide. Therefore, there is an urgent need for developing preventive and therapeutic cancer vaccines.
Hui Kian Ong, Wen Siang Tan, Kok Lian Ho
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Virus-Like Particles as an Immunogenic Platform for Cancer Vaccines
Viruses, 2020 Virus-like particles (VLP) spontaneously assemble from viral structural proteins. They are naturally biocompatible and non-infectious. VLP can serve as a platform for many potential vaccine epitopes, display them in a dense repeating array, and elicit ...
Jerri C. Caldeira +3 more
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Immunogenicity of Virus-like Particles Based on VP1 Protein of Bovine Norovirus [PDF]
Veterinary SciencesBovine Norovirus (BNoV) is a member of the enterovirus family that can cause gastroenteritis in calves. This virus poses a significant risk to calf growth and development as well as to the long-term sustainability of the cattle industry in China and ...
Zhigang Ma +13 more
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Self diffusion of particles in complex fluids: temporary cages and permanent barriers [PDF]
, 2008 We study the self diffusion of individual particles in dense (non-)uniform complex fluids within dynamic density functional theory and explicitly account for their coupling to the temporally fluctuating background particles. Applying the formalism to rod-
H. Risken +6 more
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Journal of Nanobiotechnology, 2021 Virus-like particles (VLPs) are virus-derived structures made up of one or more different molecules with the ability to self-assemble, mimicking the form and size of a virus particle but lacking the genetic material so they are not capable of infecting ...
Saghi Nooraei +6 more
semanticscholar +1 more source