Results 41 to 50 of about 167,591,039 (221)
Deep sequencing analysis of defective genomes of parainfluenza virus 5 and their role in interferon induction [PDF]
This work was supported by The Wellcome Trust (087751/A/08/Z).Preparations of parainfluenza virus 5 (PIV5) that are potent activators of the interferon (IFN) induction cascade were generated by high-multiplicity passage in order to accumulate defective ...
Killip, M. J. +13 more
core +1 more source
Root parasitic nematodes in nursery plants imported to Finland in 1980
Injurious nematodes were found in 201 of the investigated 670 plant stocks of 42 imported consignments. Infections by quarantine nematodes appeared in 100 stocks of 26 consignments, 15 there of including 3 or more infected plant stocks each.
Sirpa Kurppa
doaj
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Background: Influenza virus (IFV), respiratory syncytial virus (RSV), parainfluenza virus (PIV), and metapneumovirus (MPV) are the most common viruses associated with acute lower respiratory infections in young children and the elderly.
Nair, Harish, Li, You
core +1 more source
An unbiased genetic screen reveals the polygenic nature of the influenza virus anti-interferon response [PDF]
Influenza A viruses counteract the cellular innate immune response at several steps, including blocking RIG I-dependent activation of interferon (IFN) transcription, IFN-dependent upregulation of IFN-stimulated genes (ISGs) and the activity of various ...
Fernández, Yolanda +23 more
core +1 more source
Mediator Subunit RhMED15a Regulates Drought Tolerance in Rose
Mediator is a multiprotein complex integral to the transcription machinery, mediated by RNA polymerase II. Some Mediator subunits have been found to have critical functions in plants’ responses to abiotic stresses.
Xiaoman Shang +7 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
WREATH OF ROSES»: I. MYATLEV, I. S. TURGENEV, I. SEVERYANIN
The article is devoted to the comparative analysis of the three most famous works of the «pink» cycle: I. Myatlev's poem (1834) which marked the beginning of the «rotation of roses»; the lyrical prosaic miniature of I. S.
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Tracking Virus-Specific CD4+ T Cells during and after Acute Hepatitis C Virus Infection [PDF]
Background. CD4+ T cell help is critical in maintaining antiviral immune responses and such help has been shown to be sustained in acute resolving hepatitis C.
Paul Klenerman +175 more
core +2 more sources

