Results 251 to 260 of about 1,825,715 (311)

EIF4H and YBX1 are essential host factors for hepatitis E virus replication and pathogenesis. [PDF]

Proc Natl Acad Sci U S A
Ju X, Dong L, Liu T, Zhang F, Sun X, Schwoerer MP, Ren W, Gong M, Ploss A, Qin W, Wu X, Wang L, Ding Q.   +12 more
europepmc   +1 more source

Microprotein MP104 Promotes Malignant Progression of Colorectal Cancer Through Regulating Protein Translation

Advanced Science, EarlyView.
A previously unrecognized microprotein, MP104, encoded by ZEB1‐AS1, emerges as a critical driver of colorectal cancer progression. MP104 links ubiquitin‐mediated protein degradation with translational reprogramming via the UBE2O–AMPKα2–mTOR–EIF4B axis, revealing an unrecognized layer of oncogenic regulation.
Fang Chen, Miao Wang, Hongmei Yong, Jin Ding, Shiping Xu, Qirui Ge, Yan Wang, Lei Zhang, Qianqian Xiao, Benli Li, Li Lin, Sufang Chu, Qianqing Wang, Jin Bai, Pingfu Hou   +14 more
wiley   +1 more source

Expression of Concern: MiR-125b Reduces Porcine Reproductive and Respiratory Syndrome Virus Replication by Negatively Regulating the NF-κB Pathway. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source

Cellular miR-24-3p inhibits vaccinia virus replication by targeting kinesin-like protein KIF21B. [PDF]

Biosaf Health
Jiao P, Ran Y, Liu D, Mei L, Pang G, Liang S, Liu Y, Sun L, Wang Z, Zhang K.   +9 more
europepmc   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

Advanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li, Haimin Chen, Gangqi Fang, Dongxiang Wei, Hongyun Wu, Chen Chen, Song Hong, Chengshu Wang   +7 more
wiley   +1 more source

Nicotinamide metabolism is essential for Hepatitis C Virus replication and the production of infectious Lipo-Viro-Particles. [PDF]

PLoS Pathog
Toesca J, Castell M, Jacquemin C, Lalande A, Ogire E, Burlaud-Gaillard J, Roingeard P, Ramière C, Mathieu C, Perrin-Cocon L, Lotteau V, Vidalain PO, Diaz O.   +12 more
europepmc   +1 more source

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

Dual functions of the Aedes aegypti ecdysone receptor in dengue virus replication and reproduction control. [PDF]

Parasit Vectors
Weng SC, Lin YS, Tsao PN, Shiao SH.
europepmc   +1 more source

Brefeldin A inhibits duck plague virus replication by impairing virion envelopment. [PDF]

Poult Sci
Wang X, Tian B, Liu Z, Cai D, Tian Y, Wang M, Wu Y, Yang Q, Zhang S, Zhu D, Liu M, Zhao X, Sun D, Huang J, Ou X, Wu Z, He Y, Jia R, Chen S, Cheng A.   +19 more
europepmc   +1 more source