Results 61 to 70 of about 494,159 (263)

Multiple DNA markers for evaluation of resistance against Potato virus Y, Potato virus S and Potato leafroll virus

open access: yesCzech Journal of Genetics and Plant Breeding, 2018
Molecular markers within or close to genes of interest play essential roles in marker-assisted selection. PCR-based markers have been developed for numerous traits in different plant species including several genes conferring resistance to viruses in ...
Masoud NADERPOUR, Leila SADEGHI
doaj   +1 more source

Optimized RNA-Silencing Strategies for Rice Ragged Stunt Virus Resistance in Rice

open access: yesPlants, 2021
Rice ragged stunt virus (RRSV) is one of the most damaging viruses of the rice culture area in south and far-eastern Asia. To date, no genetic resistance has been identified and only expensive and non-environmentally friendly chemical treatments are ...
Severine Lacombe   +5 more
doaj   +1 more source

Resistance to Aphid Vectors of Virus Disease

open access: yes, 2010
The majority of plant viruses rely on vectors for their transmission and completion of their life cycle. These vectors comprise a diverse range of life forms including insects, nematodes, and fungi with the most common of these being insects. The geographic range of many of these vectors is continually expanding due to climate change.
Westwood, J. H., Stevens, M.
openaire   +2 more sources

On Resistance to Virus Entry into Host Cells [PDF]

open access: yesBiophysical Journal, 2012
In this article, we adopt a continuum model from Sun and Wirtz (2006. Biophys. J. 90:L10-L12) to show that, for the enveloped virus entry into host cells, the binding energy of the receptor-ligand complex can drive the engulfment of the viral particle to overcome the resistance alternatively dominated by the membrane deformation and cytoskeleton ...
Li, Long   +3 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Mechanisms of resistance to viruses

open access: yesPlant Protection Science, 2002
Resistance associated with a hypersensitive response (HR) and subsequent development of necrotic lesions (cell death) at the sites of virus infection can restrict virus movement in plants. Genes for HR are dominant and act on a gene-for-gene basis.
J.P.T. Valkonen
doaj   +1 more source

Characterization of Cauliflower Mosaic Virus (CaMV) Resistance in Virus-Resistant Ecotypes ofArabidopsis

open access: yesMolecular Plant-Microbe Interactions, 1996
Two Arabidopsis ecotypes are resistant to systemic infection by cauliflower mosaic virus (CaMV), a plant para-retrovirus. Arabidopsis ecotype Enkheim-2 (En-2) is highly resistant to CaMV infection while Bla-14 is more weakly resistant. CaMV resistance in En-2 can be largely attributed to the action of a single semidominant gene called cauliflower ...
A, Callaway   +7 more
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Allopolyploidy and the evolution of plant virus resistance [PDF]

open access: yesBMC Evolutionary Biology, 2014
The relationship between allopolyploidy and plant virus resistance is poorly understood. To determine the relationship of plant evolutionary history and basal virus resistance, a panel of Nicotiana species from diverse geographic regions and ploidy levels was assessed for resistance to non-coevolved viruses from the genus Nepovirus, family Secoviridae.
Gottula, John   +3 more
openaire   +2 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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