Results 161 to 170 of about 526,290 (218)

Translational Barriers and AI‐Driven Challenges of Microfluidics‐Enabled Wearables and Implantable Systems in Personalized Medicine

Advanced Science, EarlyView.
An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang, Ching Yin Fong, Xin Huang, Bee Luan Khoo   +3 more
wiley   +1 more source

Native Regiella Endosymbionts Provide Strong Parasitoid Protection With Limited Impacts on Fitness and Virus Transmission in Myzus persicae. [PDF]

Environ Microbiol
Yang Q, Ross PA, Gill A, Gu X, Durugkar N, Chang J, Holland OJ, Umina PA, Vorburger C, Kristensen TN, Hoffmann AA.   +10 more
europepmc   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source

Disentangling Temporal Trends of Clade Ib Monkeypox Virus Transmission in Burundi. [PDF]

J Infect Dis
Jin S, Asakura TR, Murayama H, Jung SM, Niyukuri D, Nyandwi J, Nkengurutse L, Kamatari O, Lim JT, Endo A, Dickens BL.   +10 more
europepmc   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Potential vectors associated to Oropouche virus transmission in Cuba, 2024. [PDF]

GigaByte
Sánchez González M, Companioni A, Camacho E, Serrano S, Álvarez M, Rodriguez-Potrony H, Alfonso Y, Liberty B, Varens J, Martínez Y, Menendez Z, Rodríguez Velázquez D, Rivera M, Lugo D, Kouri V, Guzman MG, Gutiérrez-Bugallo G.   +16 more
europepmc   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

Advanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia, Jingshang Wen, Jihang Li, Meina Feng, Yiming He, Ruojun Liu, Qian Liu, Junli Zhang, Kai Cheng, Xiangyu Zhang, Xiao Zhang   +10 more
wiley   +1 more source

Higher free-roaming dog density sustains rabies virus transmission in Haiti. [PDF]

Sci Rep
Beron AJ, Keshavamurthy R, Boutelle C, Wallace R.   +3 more
europepmc   +1 more source

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo

Advanced Science, EarlyView.
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li, Jintian Lyu, Kaitao Li, Ameya Dravid, Deepali Balasubramani, Amir H. K. Ashkezari, Hyun‐Kyu Choi, Gabriel A. Kwong, Ankur Singh, Cheng Zhu   +9 more
wiley   +1 more source

Phylodynamic reconstruction of H1N1pdm09 influenza virus transmission in Brazil: a decade of evolutionary dynamics. [PDF]

Emerg Microbes Infect
Brcko IC, de Souza VC, Jeronimo Lima AR, Pereira JS, de Araújo ESA, Valeiros APNV, Palmieri M, Nunes JA, Torres LS, Santos HO, Leite AB, Pereira FM, de Mello ALES, Brandão Nardy V, de Andrade GSM, Astete Gomez MK, Vieira LL, Roll MM, Henrique BVM, Lima Neto LG, Cristina de Oliveira E, Almeida JDPC, da Silva SF, Vasconcelos KR, Adelino TER, Guimaraes NR, Ribeiro Tomé LM, Arend LNVS, da Silva CC, Maia ACS, Mattos CB, Costa GDS, Alcântara LC, Kallás EG, Sampaio SC, Slavov SN, Giovanetti M, Elias MC.   +37 more
europepmc   +1 more source