Results 121 to 130 of about 3,207,629 (358)

Ebola virus VP35 has novel NTPase and helicase-like activities [PDF]

, 2019
Ting Shu, Tianyu Gan, Peng Bai, Xiaotong Wang, Qian Qi, Hui Zhou, Qi Cheng, Yang Qiu, Lei Yin, Jin Zhong, Xi Zhou   +10 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Early Steps in Herpes Simplex Virus Infection Blocked by a Proteasome Inhibitor [PDF]

, 2019
Seth M. Schneider, Suzanne M. Pritchard, George A. Wudiri, Chasity E. Trammell, Anthony V. Nicola   +4 more
openalex   +1 more source

A conserved set of mutations for stabilizing soluble envelope protein dimers from dengue and Zika viruses to advance the development of subunit vaccines

, 2022
Thanh T.N. Phan, Matthew G. Hvasta, Stephan T. Kudlacek, Devina Thiono, Ashutosh Tripathy, Nathan I. Nicely, Aravinda M. de Silva, Brian Kuhlman   +7 more
openalex   +1 more source

Characteristics of the microplate method of enzyme-linked immunosorbent assay for the detection of plant viruses.

Journal of General Virology, 1977
M. F. Clark, A. N. Adams
semanticscholar   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A U508C synonymous mutation in the SARS-CoV-2 deletion hotspot reduces deletion frequency and accelerates viral clearance

mBio
A deletion hotspot within the non-structural protein 1 (NSP1) gene (locus 500–532) has been observed in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes analyzed by next-generation sequencing.
Kaya Miyazaki, Akihiro Doi, Yuriko Tomita, Wataru Kamitani, Shutoku Matsuyama   +4 more
doaj   +1 more source

Stability of African swine fever virus on heat‐treated field crops

, 2020
Melina Fischer, Maarten Mohnke, Carolina Probst, Jutta Pikalo, Franz J. Conraths, Martin Beer, Sandra Blome   +6 more
openalex   +1 more source

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Science, 2007
R. Barrangou, C. Fremaux, H. Deveau, Melissa Richards, P. Boyaval, S. Moineau, D. Romero, P. Horvath   +7 more
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source