Results 131 to 140 of about 3,351,878 (358)

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Science, 2007
R. Barrangou, C. Fremaux, H. Deveau, Melissa Richards, P. Boyaval, S. Moineau, D. Romero, P. Horvath   +7 more
semanticscholar   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The Internal Structure of Influenza Virus [PDF]

, 1959
W. Frisch-NlGgemeyer
openalex   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Limitations in harnessing oral RNA interference as an antiviral strategy in Aedes aegypti

iScience
Summary: Mosquitoes, particularly Aedes aegypti, are critical vectors for globally significant pathogenic viruses. This study examines the limitations of oral RNA interference (RNAi) as a strategy to disrupt viral transmission by Ae. aegypti.
Ottavia Romoli, Annabelle Henrion-Lacritick, Hervé Blanc, Lionel Frangeul, Maria-Carla Saleh   +4 more
doaj   +1 more source

New insights in series of ligands used as SARS-CoV-2 virus inhibitors within molecular docking, molecular quantum similarity, and chemical reactivity indices frameworks

, 2022
Alejandro Morales‐Bayuelo
openalex   +1 more source

Viruses [PDF]

BMJ, 1966
openaire   +2 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Increase of Synergistic Secondary Antiviral Mutations in the Evolution of A(H1N1)pdm09 Influenza Virus Neuraminidases

Viruses
The unexpected emergence of oseltamivir-resistant A(H1N1) viruses in 2008 was facilitated in part by the establishment of permissive secondary neuraminidase (NA) substitutions that compensated for the fitness loss due to the NA-H275Y resistance ...
Susanne C. Duwe, Jeanette Milde, Alla Heider, Marianne Wedde, Brunhilde Schweiger, Ralf Dürrwald   +5 more
doaj   +1 more source

Black cat in a dark room: the absence of a directly oncogenic virus does not eliminate the role of an infectious agent in cutaneous T-cell lymphoma pathogenesis

, 2014
Brittany Dulmage, Hanping Feng, Ezra D. Mirvish, Larisa J. Geskin   +3 more
openalex   +2 more sources