Results 131 to 140 of about 2,202,818 (359)

Giant Viruses of the Kutch Desert [PDF]

open access: yes, 2014
The Kutch desert (Great Rann of Kutch, Gujarat, India) is a unique ecosystem: in the larger part of the year it is a hot, salty desert that is flooded regularly in the Indian monsoon season.
Grolmusz, Vince, Kerepesi, Csaba
core  

Newcastle disease virus as an antineoplastic agent [PDF]

open access: bronze, 1965
William A. Cassel, R. Earl Garrett
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Comparison of Vero and MDCK cell lines transfected with human siat7e gene for conversion to suspension culture

open access: yesVaccine Research, 2015
Introduction: Inactivated influenza vaccines are traditionally produced in chicken embryonated eggs but its limitations in producing the required doses in pandemic outbreaks quickly enough has made searching for alternative modes of production necessary.
P Mehrbod   +4 more
doaj  

Different populations of A(H1N1)pdm09 viruses in a patient with hemolytic-uremic syndrome

open access: yesInternational Journal of Medical Microbiology
Respiratory viral infections may have different impacts ranging from infection without symptoms to severe disease or even death though the reasons are not well characterized.A patient (age group 5–15 years) displaying symptoms of hemolytic uremic ...
Yuguang Fu   +17 more
doaj   +1 more source

Molecular characterization of Euphorbia caput-medusae stunt virus: Evidence for the existence of a new genus within the family Geminiviridae [PDF]

open access: yes, 2013
Studies focusing on phytoviruses isolated from the wild are rare. Nevertheless, even if those studies remain scarce, it is increasingly accepted that viruses coming from wild plants might play a role on disease emergence and in the functioning of ...
Bernardo, Pauline   +7 more
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Virus evolution : the emergence of new ideas (and re-emergence of old ones)

open access: yes, 2006
Reputed intractable, the question of the origin of viruses has long been neglected. In the modern literature 'Virus evolution' has come to refer to study more akin to population genetics, such as the world-wide scrutiny on new polymorphisms appearing ...
Claverie, Jean-Michel
core  

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