Results 71 to 80 of about 1,528,220 (309)

Characteristics of two zoonotic swine influenza A(H1N1) viruses isolated in Germany from diseased patients

International Journal of Medical Microbiology
Interspecies transmission of influenza A viruses (IAV) from pigs to humans is a concerning event as porcine IAV represent a reservoir of potentially pandemic IAV.
Alla Heider, Marianne Wedde, Viola Weinheimer, Stephanie Döllinger, Masyar Monazahian, Ralf Dürrwald, Thorsten Wolff, Brunhilde Schweiger   +7 more
doaj   +1 more source

Mother-to-Child Transmission of HTLV-1 Epidemiological Aspects, Mechanisms and Determinants of Mother-to-Child Transmission

Viruses, 2016
Human T-cell Lymphotropic Virus type 1 (HTLV-1) is a human retrovirus that infects at least 5–10 million people worldwide, and is the etiological agent of a lymphoproliferative malignancy; Adult T-cell Leukemia/Lymphoma (ATLL); and a chronic ...
Florent Percher, Patricia Jeannin, Sandra Martin-Latil, Antoine Gessain, Philippe V. Afonso, Aurore Vidy-Roche, Pierre-Emmanuel Ceccaldi   +6 more
doaj   +1 more source

Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine [PDF]

, 2014
Swine influenza A virus is an endemic and economically important pathogen in pigs, with the potential to infect other host species. The hemagglutinin (HA) protein is the primary target of protective immune responses and the major component in swine ...
A. L. Vincent, Anderson, Bao, Bowman, Brown, Centers for Disease Control and Prevention, Core Team R, D. F. Burke, Darriba, De Jong, E. Skepner, Edgar, Feng, Fouchier, Garten, Gauger, Harmon, Hinshaw, Houser, Karasin, Kawaoka, Khurana, Kitikoon, Koel, Lewis, Lindstrom, Lorusso, Loving, Maddison, Miller, Montalvao, Myers, N. S. Lewis, Nelson, Nelson, Nfon, Olsen, P. Kitikoon, Paradis, Pena, Polewicz, PyMOL, Röhm, Salmon, Shinde, Skowronski, Smith, Smith, Stamatakis, T. K. Anderson, Tong, Tong, Vincent, Vincent, Vincent, Vincent, Webby, Webby, Ye   +58 more
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

At the mercy of viruses

eLife, 2016
Viruses are responsible for many of the adaptive mutations in the human genome.
Claus O Wilke, Sara L Sawyer
openaire   +4 more sources

Molecular characterization of Secoviridae and Potexvirus infecting yams (Dioscorea spp) [PDF]

, 2011
The prevalence of virus species is generally high among vegetatively?propagated crops, because they cannot be sanitized via seed production and therefore accumulate viruses over long periods of time.
Anzala, Fabiola, Filloux, Denis, Gomez, Rose-Marie, Pavis, Claudie, Roumagnac, Philippe, Teycheney, Pierre-Yves   +5 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Association of IFITM3 rs12252 polymorphisms, BMI, diabetes, and hypercholesterolemia with mild flu in an Iranian population

Virology Journal, 2017
Background IFITM3 has been suggested to be associated with infection in some ethnic groups. Diabetes and hypercholesterolemia are also important clinical conditions that can predispose individuals to infection.
Parvaneh Mehrbod, Sana Eybpoosh, Fatemeh Fotouhi, Hadiseh Shokouhi Targhi, Vahideh Mazaheri, Behrokh Farahmand   +5 more
doaj   +1 more source

Prevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Antibodies in Egyptian Convalescent Plasma Donors

Frontiers in Microbiology, 2020
Using convalescent plasma as immunotherapy is an old method for treatment of infectious diseases. Several countries have recently allowed the use of such therapy for the treatment of COVID-19 patients especially those who are critically ill.
Mokhtar R. Gomaa, Ahmed Kandeil, Ahmed Mostafa, Wael H. Roshdy, Ahmed E. Kayed, Mahmoud Shehata, Omnia Kutkat, Yassmin Moatasim, Ahmed El Taweel, Sara H. Mahmoud, Mina Nabil Kamel, Noura M. Abo Shama, Mohamed El Sayes, Rabeh El-Shesheny, Osama H. Bakheet, Mohamed A. Elgohary, Mohamed Elbadry, Naguib N. Nassif, Salwa H. Ahmed, Ibrahim Y. Abdel Messih, Ghazi Kayali, Ghazi Kayali, Mohamed A. Ali   +22 more
doaj   +1 more source

Lineage A betacoronavirus NS2 proteins and the homologous torovirus Berne pp1a carboxy-terminal domain are phosphodiesterases that antagonize activation of RNase L [PDF]

, 2017
Viruses in the family Coronaviridae, within the order Nidovirales, are etiologic agents of a range of human and animal diseases, including both mild and severe respiratory diseases in humans.
Chen, Annie I, Elliott, Ruth, Goldstein, Stephen A, Jha, Babal K, Li, Yize, Quiroz-Figueroa, Katherine, Silverman, Robert H, Thornbrough, Joshua M, Weiss, Susan R, Zhang, Rong   +9 more
core   +2 more sources