Results 71 to 80 of about 1,996,758 (380)
(1) Background: Drug repositioning is an unconventional drug discovery approach to explore new therapeutic benefits of existing drugs. Currently, it emerges as a rapid avenue to alleviate the COVID-19 pandemic disease.
Ahmed Mostafa+19 more
doaj +1 more source
Slowly replicating lytic viruses: pseudolysogenic persistence and within-host competition [PDF]
We study the population dynamics of lytic viruses which replicate slowly in dividing host cells within an organism or cell culture, and find a range of viral replication rates that allows viruses to persist, avoiding extinction of host cells or dilution of viruses at too rapid or too slow viral replication.
arxiv +1 more source
A systematic review of emerging respiratory viruses at the Hajj and possible coinfection with Streptococcus pneumoniae [PDF]
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A.+2 more
core +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Influenza A viruses (H1N1) have been consistently one of the most evolving viruses that escape from vaccine-induced immunity. Although there has been a rapid rise in human influenza virus knowledge since the 2009 pandemic, the molecular information about
Sina Moeini+4 more
doaj
Background IFITM3 has been suggested to be associated with infection in some ethnic groups. Diabetes and hypercholesterolemia are also important clinical conditions that can predispose individuals to infection.
Parvaneh Mehrbod+5 more
doaj +1 more source
In recent years, different computing models have emerged within the area of Unconven-tional Computation, and more specifically within Natural Computing, getting inspiration from mechanisms present in Nature.
Chen, Xu+4 more
core
Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States [PDF]
Several lineages of influenza A viruses (IAV) currently circulate in North American pigs. Genetic diversity is further increased by transmission of IAV between swine and humans and subsequent evolution.
Anderson, T K+5 more
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
The pandemic of viruses with a long incubation phase in the small world [PDF]
A model of the spread of viruses in selected city and in a network of cities is considered, taking into account the delay caused by the long incubation period of the virus. The effect of delay effects is shown in comparison with pandemics without such delay. A temporary asymmetry of the spread of infection has been identified, which means that the time
arxiv