Results 51 to 60 of about 183,360 (258)

GREM2 is associated with human central obesity and inhibits visceral preadipocyte browning

EBioMedicine, 2022
Summary: Background: Some circulating proteins are linked to central adiposity. Gremlin 2 (GREM2) functions as a secreted factor involved in osteogenesis and adipogenesis. Here, we investigated the association of blood GREM2 levels and central adiposity,
Wen Liu, Danjie Li, Minglan Yang, Long Wang, Yu Xu, Na Chen, Zhiyin Zhang, Juan Shi, Wen Li, Shaoqian Zhao, Aibo Gao, Yufei Chen, Qinyun Ma, Ruizhi Zheng, Shujing Wu, Yifei Zhang, Yuhong Chen, Shuwen Qian, Yufang Bi, Weiqiong Gu, Qiqun Tang, Guang Ning, Ruixin Liu, Weiqing Wang, Jie Hong, Jiqiu Wang   +25 more
doaj   +1 more source

Patient characteristics according to the subcutaneous and visceral adiposity status.

, 2020
Patient characteristics according to the subcutaneous and visceral adiposity status.
Ngan Ming Tsang (8379438), Shu Chen Liu (8379459), Chi Cheng Chuang (8379441), Wen Ching Chuang (8379435), Kai Ping Chang (8379444), Ping Ching Pai (8379447), Kuan Hung Chen (8379450), Kin Fong Lei (467697), Wen Chi Chou (8379453), Shiao Fwu Tai (8379456)   +9 more
core   +1 more source

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

Advanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

Cardiometabolic index predicts postoperative atrial fibrillation after isolated CABG: ROC-based comparison with BMI and visceral adiposity indices

Biomolecules & Biomedicine
The assessment of visceral adipose tissue activity has gained significance in cardiac risk stratification. This study evaluates the predictive performance of novel visceral adiposity indices in determining the risk of postoperative atrial fibrillation ...
Ercan Kahraman, Şirin Cetin
doaj   +1 more source

Increased circulating chemerin in patients with advanced carotid stenosis

BMC Cardiovascular Disorders, 2018
Background Chemerin is an adipokine which plays a crucial role in atherosclerosis. Here, we examined whether circulating chemerin is enhanced in patients with advanced carotid stenosis. Methods Chemerin was quantified in 178 patients prior to carotid end
Adrian Kammerer, Holger Staab, Maria Herberg, Christine Kerner, Nora Klöting, Gabriela Aust   +5 more
doaj   +1 more source

Adiposity, adipokines, and risk of incident stroke in older men [PDF]

, 2013
<p>Background and Purpose—The association between adiposity and adipocytes and risk of stroke in older adults is uncertain. We have examined the association between adiposity measures and adipocytes (adiponectin and leptin) with incident stroke ...
Shaper, A.G., Whincup, P.H., Lennon, L., Sattar, N., Wannamethee, S.G.   +4 more
core   +1 more source

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

Advanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang, Wenhui Xie, Lei Yang, Zhengrong Wang, Yi Huang, Peng Huang, Yuan Liu, Jun Hu   +7 more
wiley   +1 more source

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

Advanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang, Yangfan Huo, Jin Liu, Sida Liu, Minghai Ma, Hao Guo, Yuanquan Zhang, Xing Li, Xiao Liang, Jiawei Xiu, Ying Sun, Lijun Huang, Xiaolong Yan, Weiwei Wu, Lei Wang   +14 more
wiley   +1 more source

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

Advanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury, Xuanyi Lin, Peter D. Rios, Christopher Olker, Eun Joo Song, Alejandra Cobos Perez, Cody Fell, Daisy Lopez, Ira Joshi, Hafsa Nasir, Cecelia Curtis, Danna Muringi, Kaiyuan Wang, José Oberholzer, Fred W. Turek, Isaac B. Hilton, Jonathan Rivnay, Martha Hotz Vitaterna, Omid Veiseh   +18 more
wiley   +1 more source

Role of visceral adiposity in functional recovery after myocardial infarction in females

Journal of Education, Health and Sport
Title: Visceral Adiposity and Functional Recovery After Myocardial Infarction in Obese Female Patients: A Prospective Cohort Study Background: Visceral adiposity is increasingly recognized as a critical determinant of myocardial infarction (MI ...
Yu. Zhukova, M. Zak
doaj   +1 more source