Results 191 to 200 of about 216,511 (353)

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Externalized Inflammasomes in Visceral Fat Sustain Obesity-Related Inflammation. [PDF]

Circ Res
Wissemann J, Heidenreich A, Suchanek D, Koentges C, Engelmann J, Jung M, Karnbrock L, Marchini T, Pospisilik A, Seifert G, Groß O, Gissler MC, Hilgendorf I, von Zur Mühlen C, Zirlik A, Westermann D, Stachon P, Wolf D, Merz J.   +18 more
europepmc   +1 more source

Addressing Heterogeneity in Binge Eating Disorder: A Cluster Analysis Approach Based on Age of Onset, Clinical and Psychopathological Features

European Eating Disorders Review, EarlyView.
ABSTRACT Objective This study investigates clinical heterogeneity in patients with binge eating disorder (BED) and its association with treatment outcomes. Methods A two‐step cluster analysis was conducted on a clinical sample of 196 BED patients, using an agglomerative hierarchical procedure based on both categorical and quantitative measures ...
Lucía Camacho‐Barcia, Lia T. Sánchez‐Salido, Jessica Jiménez del Toro, Roser Granero, Isabel Sánchez, Kim Supit, Nadia Micali, Katrin Elisabeth Giel, Susana Jiménez‐Murcia, Stephan Zipfel, Fernando Fernández‐Aranda   +10 more
wiley   +1 more source

Correction: Effect of visceral fat on onset of metabolic syndrome. [PDF]

Sci Rep
Bushita H, Ozato N, Mori K, Kawada H, Katsuragi Y, Osaki N, Mikami T, Itoh K, Murashita K, Nakaji S, Tamada Y.   +10 more
europepmc   +1 more source

Patients with MAC Lung Disease Have a Low Visceral Fat Area and Low Nutrient Intake [PDF]

, 2015
Kentaro Wakamatsu, Nobuhiko Nagata, Sanae Maki, Hisamitsu Omori, Hiroyuki Kumazoe, K. Ueno, Yuko Matsunaga, Makiko Hara, Koji Takakura, Nagisa Fukumoto, Nobuhisa Ando, Mami Morishige, Takashi Akasaki, Ichiro Inoshima, Shinji Ise, Miiru Izumi, Masayuki Kawasaki   +16 more
openalex   +1 more source

Sarcopenia and excess visceral fat accumulation negatively affect early urinary function after I‐125 low‐dose‐rate brachytherapy for localized prostate cancer

, 2022
Naoyuki Ogasawara, Makoto Nakiri, Hirofumi Kurose, Kosuke Ueda, Katsuaki Chikui, Kiyoaki Nishihara, Mitsunori Matsuo, Shigetaka Suekane, Yoshitaka Morimatsu, Kenta Murotani, Koichiro Muraki, Chikayuki Hattori, Etsuyo Ogo, Tatsuya Ishitake, Tsukasa Igawa   +14 more
openalex   +1 more source

Peach Kernel Oil Modulates Lipid Metabolism Disorder in ApoEa CRISPR/Cas9 Gene‐Disrupted Zebrafish

Food Frontiers, EarlyView.
In this study, we used CRISPR/Cas9 gene editing technology to establish a lipid metabolism disorder model of ApoEa mutant zebrafish. We applied peach kernel oil to this model and studied the mechanism of peach kernel oil regulating lipid disorder in combination with transcriptomics.
Lei Xia, Yuemi Mo, Yuntian Duan, Hu Liang, Yulu Li, Wanruo Wan, Minghuang Luo, Qianhua Li, Xueni Wang, Qing Chen, Zhengcai Du, Xiaotao Hou, Fan Zhang, Jiagang Deng, Erwei Hao   +14 more
wiley   +1 more source

Metabolic score for visceral fat and atrial fibrillation risk: a prospective study. [PDF]

BMC Endocr Disord
Duan C, Zhang W, Shi J, Yang Y, Shi S, Chu Y, Hu Y.   +6 more
europepmc   +1 more source

Visceral Fat and Adiponectin: Associations with Insulin Resistance Are Tissue-Specific in Women

, 2008
Robert H. Coker, Rick H. Williams, Sophie E. Yeo, Patrick Kortebein, Don L. Bodenner, Philip A. Kern, William J. Evans   +6 more
openalex   +1 more source

Guideline for the In Vivo Immunomodulatory Activity Test of Polysaccharide Based on Cyclophosphamide‐Induced Mouse Model

Food Safety and Health, EarlyView.
Abstract graph of the in vivo immunomodulatory activity of polysaccharide based on a cyclophosphamide‐induced mouse model. ABSTRACT The immune system serves as the primary defense mechanism against pathogens and plays a vital role in maintaining host homeostasis. In recent years, natural polysaccharides have emerged as promising immunomodulators due to
Wenlei Nie, Xuecong Tong, Qiao Ding, Xiaojun Huang   +3 more
wiley   +1 more source