Results 241 to 250 of about 309,484 (272)

Early-life stress induces visceral hypersensitivity in mice

Neuroscience Letters, 2012
Early-life stress is a risk factor for irritable bowel syndrome (IBS), a common and debilitating functional gastrointestinal disorder that is often co-morbid with stress-related psychiatric disorders. In the rat, maternal separation (MS) stress has been shown to induce visceral hypersensitivity in adulthood and thus has become a useful model of IBS ...
Moloney, Rachel D., O'Leary, Olivia F., Felice, Daniela, Bettler, Bernhard, Dinan, Timothy G., Cryan, John F.   +5 more
openaire   +3 more sources

Irritable pouch syndrome is characterized by visceral hypersensitivity

Inflammatory Bowel Diseases, 2011
Irritable pouch syndrome (IPS) is a functional disorder in patients with ileal pouch-anal anastomosis (IPAA), which presents with symptoms in the absence of structural abnormalities of the pouch. Thus, it resembles other functional disorders, such as irritable bowel syndrome characterized by visceral hypersensitivity in the presence of normal rectal ...
Bo, Shen, Claudia, Sanmiguel, Ana E, Bennett, Lei, Lian, Brett, Larive, Feza H, Remzi, Victor W, Fazio, Edy E, Soffer   +7 more
openaire   +2 more sources

P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivity

Gut, 2008
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterised by abdominal pain and bloating in association with altered bowel movements. Its pathogenesis and the underlying molecular mechanisms of visceral hyperalgesia remain elusive. Recent studies of somatic and other visceral pain models suggest a role for purinergic signalling
G-Y, Xu, M, Shenoy, J H, Winston, S, Mittal, P J, Pasricha   +4 more
openaire   +2 more sources

Visceral Hypersensitivity in Functional Dyspepsia (FD): Therapeutic Approaches to FD Based on Suppression of Visceral Hypersensitivity

2018
Visceral hypersensitivity is an important mechanism in the development of functional gastrointestinal disorders (FGID), including irritable bowel syndrome (IBS), noncardiac disorder, and functional dyspepsia (FD). In pathophysiology of FD, visceral hypersensitivity in gastric distension is a main mechanism in addition to gastric motor dysfunction ...
Yasuhito Uezono, Kanako Miyano
openaire   +1 more source

Visceral hypersensitivity and impaired accommodation in refractory diabetic gastroparesis

Neurogastroenterology & Motility, 2008
Abstract  The pathophysiology of persistent gastrointestinal (GI) symptoms in patients with diabetic gastroparesis is poorly understood. Our aim was to evaluate gastric sensation and accommodation to a meal in patients with diabetic gastroparesis and refractory symptoms.
A, Kumar, A, Attaluri, S, Hashmi, K S, Schulze, S S C, Rao   +4 more
openaire   +2 more sources

Review article: visceral hypersensitivity.

Alimentary pharmacology & therapeutics, 2003
Visceral hypersensitivity is highly prevalent in all functional bowel disorders. Most also demonstrate wider patterns of somatic referral of intestinal pain or discomfort. This hypersensitivity may explain the symptoms as the sensitive gut can be more easily provoked by normal or abnormal motor events in the gut.
openaire   +1 more source

Parental Care, Mast Cells and Visceral Hypersensitivity

Journal of Pediatric Gastroenterology and Nutrition, 2005
van den Wijngaard, René, Welting, Olaf, de Jonge, Wouter, Boeckxstaens, Guy   +3 more
openaire   +2 more sources

Gut enterochromaffin cells drive visceral pain and anxiety

Nature, 2023
James R Bayrer, Holly A Ingraham, Stuart Brierley   +2 more
exaly  

Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?

Nature Reviews Microbiology, 2007
François Chappuis, Shyam Sundar, Marleen Boelaert   +2 more
exaly   +2 more sources

Selective targeting of visceral adiposity by polycation nanomedicine

Nature Nanotechnology, 2022
, Tianyu Li, Yang Xiao
exaly