Results 11 to 20 of about 184,446 (291)
Microbiota regulates visceral pain in the mouse [PDF]
eLife, 2017 The perception of visceral pain is a complex process involving the spinal cord and higher order brain structures. Increasing evidence implicates the gut microbiota as a key regulator of brain and behavior, yet it remains to be determined if gut bacteria ...
Pauline Luczynski +7 more
doaj +6 more sources
Alterations in prefrontal-limbic functional activation and connectivity in chronic stress-induced visceral hyperalgesia. [PDF]
, 2013 Repeated water avoidance stress (WAS) induces sustained visceral hyperalgesia (VH) in rats measured as enhanced visceromotor response to colorectal distension (CRD).
Bota, Mihail +6 more
core +11 more sources
NONORGANIC PAIN AND VISCERAL HYPERALGESIA IN CHILDHOOD [PDF]
Romanian Journal of Pediatrics, 2013 Visceral pain is different from the somatic one: visceral receptors have different functional engagement, the nociception degree differ from one organ to another, the few visceral afferent fi bers are predominantly unmyelinised and have an extensive ...
Ileana Ioniuc +2 more
doaj +1 more source
Possible implications of animal models for the assessment of visceral pain
Animal Models and Experimental Medicine, 2020 Acute pain, provoked generally after the activation of peripheral nociceptors, is an adaptive sensory function that alerts the individual to avoid noxious stimuli.
Bharata Regmi, Manoj K. Shah
doaj +1 more source
Animal models of visceral pain and the role of the microbiome
Neurobiology of Pain, 2021 Visceral pain refers to pain arising from the internal organs and is distinctly different from the expression and mechanisms of somatic pain. Diseases and disorders with increased visceral pain are associated with significantly reduced quality of life ...
Christine West, Karen-Anne McVey Neufeld
doaj +1 more source
P2Y Receptors Sensitize Mouse and Human Colonic Nociceptors [PDF]
, 2016 Activation of visceral nociceptors by inflammatory mediators contributes to visceral hypersensitivity and abdominal pain associated with many gastrointestinal disorders.
Baker, MD +11 more
core +1 more source
Estrous cycle influences excitatory amino acid transport and visceral pain sensitivity in the rat: Effects of early-life stress [PDF]
, 2016 Background: Early-life stress (ELS) is a recognized risk factor for chronic pain disorders, and females appear to be more sensitive to the negative effects of stress.
Cryan, John F. +6 more
core +1 more source
Visceral pain: gut microbiota, a new hope?
Journal of Biomedical Science, 2018 Background Visceral pain is a complex and heterogeneous disorder, which can range from the mild discomfort of indigestion to the agonizing pain of renal colic. Regulation of visceral pain involves the spinal cord as well as higher order brain structures.
Matteo M Pusceddu, Melanie G Gareau
doaj +1 more source
Brain Sciences, 2023 Neonatal maternal separation (NMS) is an early-life stress (ELS) that can result in adult visceral hypersensitivity, which is usually manifested as chronic visceral pain.
Ziyang Chen +5 more
doaj +1 more source
Acta Neuropathologica Communications, 2023 Unlike physiological stress, which carries survival value, pathological stress is widespread in modern society and acts as a main risk factor for visceral pain.
Dexu Kong +10 more
doaj +1 more source