Results 11 to 20 of about 86,688 (248)

Visceral pain from neuroanatomy to receptors – focus on gastrointestinal pain [PDF]

open access: yesRomanian Journal of Neurology, 2016
The mechanisms and nervous structures involved in visceral pain are poorly understood, although visceral pain is one of the most debilitating clinical types of pain.
Teodora Alexa-Stratulat   +2 more
doaj   +1 more source

Greater interruption of visual processing and memory encoding by visceral than somatic pain in healthy volunteers – An fMRI study

open access: yesNeuroImage, 2022
Visceral pain is regarded as more salient than somatic pain. It has greater affective and emotional components, i.e., it elicits higher levels of pain-related fear and is perceived as more unpleasant than somatic pain. In this fMRI study, we examined the
Katharina Schmidt   +6 more
doaj   +1 more source

Disengaging spinal afferent nerve communication with the brain in live mice

open access: yesCommunications Biology, 2022
A surgical method in mice can selectively remove dorsal root ganglia (DRG) at specific spinal levels without interfering with other nerves, providing insight on thoracolumbar vs. lumbosacral DRG contributions to pain signalling and behaviour.
Melinda A. Kyloh   +9 more
doaj   +1 more source

NONORGANIC PAIN AND VISCERAL HYPERALGESIA IN CHILDHOOD [PDF]

open access: yesRomanian Journal of Pediatrics, 2013
Visceral pain is different from the somatic one: visceral receptors have different functional engagement, the nociception degree differ from one organ to another, the few visceral afferent fi bers are predominantly unmyelinised and have an extensive ...
Ileana Ioniuc   +2 more
doaj   +1 more source

Visceral pain: gut microbiota, a new hope?

open access: yesJournal of Biomedical Science, 2018
Background Visceral pain is a complex and heterogeneous disorder, which can range from the mild discomfort of indigestion to the agonizing pain of renal colic. Regulation of visceral pain involves the spinal cord as well as higher order brain structures.
Matteo M Pusceddu, Melanie G Gareau
doaj   +1 more source

Animal models of visceral pain and the role of the microbiome

open access: yesNeurobiology of Pain, 2021
Visceral pain refers to pain arising from the internal organs and is distinctly different from the expression and mechanisms of somatic pain. Diseases and disorders with increased visceral pain are associated with significantly reduced quality of life ...
Christine West, Karen-Anne McVey Neufeld
doaj   +1 more source

Paraventricular Mast Cell-Derived Histamine Activates CRH Neurons to Mediate Adult Visceral Hypersensitivity Induced by Neonatal Maternal Separation

open access: yesBrain Sciences, 2023
Neonatal maternal separation (NMS) is an early-life stress (ELS) that can result in adult visceral hypersensitivity, which is usually manifested as chronic visceral pain.
Ziyang Chen   +5 more
doaj   +1 more source

The locus coeruleus input to the rostral ventromedial medulla mediates stress-induced colorectal visceral pain

open access: yesActa Neuropathologica Communications, 2023
Unlike physiological stress, which carries survival value, pathological stress is widespread in modern society and acts as a main risk factor for visceral pain.
Dexu Kong   +10 more
doaj   +1 more source

Paclitaxel—A Valuable Tool for Inducing Visceral Pain in Preclinical Testing?

open access: yesInternational Journal of Translational Medicine, 2023
Visceral pain is a unique clinical entity that lacks an effective and safe treatment. Proper preclinical models are essential for assessing new drugs developed for the treatment of this pathology.
Corina Andrei   +3 more
doaj   +1 more source

Stress-Induced Chronic Visceral Pain of Gastrointestinal Origin

open access: yesFrontiers in Systems Neuroscience, 2017
Visceral pain is generally poorly localized and characterized by hypersensitivity to a stimulus such as organ distension. In concert with chronic visceral pain, there is a high comorbidity with stress-related psychiatric disorders including anxiety and ...
Beverley Greenwood-Van Meerveld   +3 more
doaj   +1 more source

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